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    nob1 NIN1 (RPN12) binding protein 1 homolog [ Danio rerio (zebrafish) ]

    Gene ID: 557254, updated on 27-Mar-2024

    Summary

    Official Symbol
    nob1provided by ZNC
    Official Full Name
    NIN1 (RPN12) binding protein 1 homologprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3112
    See related
    Ensembl:ENSDARG00000016080 AllianceGenome:ZFIN:ZDB-GENE-030131-3112
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    Nob1p; fc27e05; wu:fc27e05; si:ch73-167i17.3
    Summary
    Predicted to enable endoribonuclease activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to act upstream of or within cleavage involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in nucleus. Predicted to be part of preribosome, small subunit precursor. Orthologous to human NOB1 (NIN1 (RPN12) binding protein 1 homolog). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See nob1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (5860217..5875241, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (5245302..5260449, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene NIP7 nucleolar pre-rRNA processing protein Neighboring gene component of oligomeric golgi complex 8 Neighboring gene WD repeat domain 59 Neighboring gene golgi glycoprotein 1b Neighboring gene zinc finger homeobox 3a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within ribosomal small subunit biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of preribosome, small subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    RNA-binding protein NOB1
    Names
    nin one binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      5860217..5875241 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021467739.1XP_021323414.1  RNA-binding protein NOB1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PFN4
      Conserved Domains (2) summary
      cd09876
      Location:9112
      PIN_Nob1; PIN domain of eukaryotic ribosome assembly factor Nob1 and archaeal UPF0129 protein Ta0041-like homologs
      pfam08772
      Location:244316
      NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like
    2. XM_678662.9XP_683754.2  RNA-binding protein NOB1 isoform X1

      UniProtKB/TrEMBL
      A0A8N7TEG7, I3ISV3
      Related
      ENSDARP00000125998.2, ENSDART00000151727.2
      Conserved Domains (3) summary
      cd09876
      Location:9112
      PIN_Nob1; PIN domain of eukaryotic ribosome assembly factor Nob1 and archaeal UPF0129 protein Ta0041-like homologs
      pfam15017
      Location:140249
      AF1Q; Drug resistance and apoptosis regulator
      pfam08772
      Location:289361
      NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like
    3. XM_009293382.2XP_009291657.1  RNA-binding protein NOB1 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AUP7
      Conserved Domains (3) summary
      pfam15017
      Location:69178
      AF1Q; Drug resistance and apoptosis regulator
      pfam08772
      Location:218290
      NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like
      cl14812
      Location:178253
      PIN_SF; PIN (PilT N terminus) domain: Superfamily