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    Zfp53 zinc finger protein 53 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308236, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Zfp53provided by RGD
    Official Full Name
    zinc finger protein 53provided by RGD
    Primary source
    RGD:1308573
    See related
    Ensembl:ENSRNOG00000042347 AllianceGenome:RGD:1308573
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Thymus (RPKM 75.1), Spleen (RPKM 63.6) and 9 other tissues See more
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    Genomic context

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    See Zfp53 in Genome Data Viewer
    Location:
    1q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (69956965..69987297)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (61284016..61313242)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (61348278..61377590)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120099215 Neighboring gene zinc finger protein 54-like Neighboring gene transfer RNA arginine (anticodon CCU) 1 Neighboring gene ribonuclease H2, subunit B, pseudogene 1 Neighboring gene uncharacterized LOC102547319 Neighboring gene uncharacterized LOC134482874 Neighboring gene zinc finger protein 52 Neighboring gene zinc finger protein 948

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 53

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107468.2 → NP_001100938.1  zinc finger protein 53

      See identical proteins and their annotated locations for NP_001100938.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6KB94, D3ZN28
      Related
      ENSRNOP00000015343.7, ENSRNOT00000015343.8
      Conserved Domains (3) summary
      COG5048
      Location:208 → 614
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:493 → 513
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:44 → 84
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      69956965..69987297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063288599.1 → XP_063144669.1  zinc finger protein 53 isoform X1

      UniProtKB/TrEMBL
      A6KB96
    Nucleotide Protein Strain
    Heading Accession and Version

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