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    Zfp764 zinc finger protein 764 [ Mus musculus (house mouse) ]

    Gene ID: 233893, updated on 30-Apr-2024

    Summary

    Official Symbol
    Zfp764provided by MGI
    Official Full Name
    zinc finger protein 764provided by MGI
    Primary source
    MGI:MGI:2443580
    See related
    Ensembl:ENSMUSG00000045757 AllianceGenome:MGI:2443580
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    8030466O12Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus; genitourinary system; heart; and limb. Orthologous to human ZNF764 (zinc finger protein 764). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 1.7), lung adult (RPKM 1.7) and 28 other tissues See more
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    Genomic context

    See Zfp764 in Genome Data Viewer
    Location:
    7 F3; 7 69.5 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126975978..127006005, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127379762..127406835, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9710 Neighboring gene ferredoxin 1-like pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E9711 Neighboring gene zinc finger protein 747 Neighboring gene zinc finger protein 747 like 1 Neighboring gene STARR-positive B cell enhancer ABC_E4978 Neighboring gene zinc finger protein 764 like 1 Neighboring gene STARR-positive B cell enhancer ABC_E4979 Neighboring gene SMT3 suppressor of mif two 3 homolog 2, pseudogene 2 (S. cerevisiae) Neighboring gene myeloma-overexpressed gene 2 protein homolog Neighboring gene STARR-seq mESC enhancer starr_20181 Neighboring gene zinc finger protein 688

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Clone Names

    • MGC31213

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription coregulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to glucocorticoid stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001167832.1NP_001161304.1  zinc finger protein 764 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 5' coding region, compared to variant 1. This difference results in a frameshift and a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK042873, AK053795
      UniProtKB/TrEMBL
      Q8C964
      Related
      ENSMUST00000139118.2
      Conserved Domains (1) summary
      pfam01352
      Location:2249
      KRAB; KRAB box
    2. NM_146203.4NP_666315.3  zinc finger protein 764 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform 1.
      Source sequence(s)
      AK042873, AK053795
      Consensus CDS
      CCDS21865.1
      UniProtKB/TrEMBL
      E9QAP1, Q8C964
      Related
      ENSMUSP00000052944.7, ENSMUST00000059199.7
      Conserved Domains (6) summary
      smart00349
      Location:2281
      KRAB; krueppel associated box
      COG5048
      Location:178243
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:154174
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:321343
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:2255
      KRAB; KRAB box
      pfam13465
      Location:335360
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      126975978..127006005 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_869713.4 RNA Sequence