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    Bet1 Bet1 golgi vesicular membrane trafficking protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29631, updated on 2-May-2024

    Summary

    Official Symbol
    Bet1provided by RGD
    Official Full Name
    Bet1 golgi vesicular membrane trafficking proteinprovided by RGD
    Primary source
    RGD:2203
    See related
    AllianceGenome:RGD:2203
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables syntaxin binding activity. Involved in vesicle fusion with Golgi apparatus. Acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi cis cisterna and cis-Golgi network. Is integral component of membrane. Part of SNARE complex. Orthologous to human BET1 (Bet1 golgi vesicular membrane trafficking protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Liver (RPKM 355.6), Kidney (RPKM 181.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Bet1 in Genome Data Viewer
    Location:
    4q13
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (33070892..33081162, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (32116232..32126592, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (29082368..29092638, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350669 Neighboring gene G protein subunit gamma 11 Neighboring gene uncharacterized LOC102557375 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing protein 2-like 2, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC72488

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables syntaxin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi cis cisterna IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi cisterna IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SNARE complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of SNARE complex TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    BET1 homolog
    Names
    Golgi vesicular membrane-trafficking protein p18
    golgi vesicular membrane trafficking protein p18
    rBET1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019251.2NP_062124.1  BET1 homolog

      See identical proteins and their annotated locations for NP_062124.1

      Status: PROVISIONAL

      Source sequence(s)
      BC062408
      UniProtKB/Swiss-Prot
      Q62896
      UniProtKB/TrEMBL
      A0A8I6ANQ2, A6K2B6
      Conserved Domains (1) summary
      cd15853
      Location:2987
      SNARE_Bet1; SNARE motif of Bet1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      33070892..33081162 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)