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    pfdn4 prefoldin subunit 4 [ Danio rerio (zebrafish) ]

    Gene ID: 572231, updated on 11-Apr-2024

    Summary

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    Official Symbol
    pfdn4provided by ZNC
    Official Full Name
    prefoldin subunit 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-100922-122
    See related
    Ensembl:ENSDARG00000061228 AllianceGenome:ZFIN:ZDB-GENE-100922-122
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-222e15.2
    Summary
    Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be part of prefoldin complex. Predicted to be active in cytoplasm. Orthologous to human PFDN4 (prefoldin subunit 4). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See pfdn4 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (38151065..38160023, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (38219954..38228591, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene si:dkey-222e15.4 Neighboring gene transfer RNA threonine (anticodon UGU) Neighboring gene zgc:112994 Neighboring gene zinc finger protein 217 Neighboring gene teashirt zinc finger homeobox 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of prefoldin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of prefoldin complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    prefoldin subunit 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386509.1 → NP_001373438.1  prefoldin subunit 4

      Status: VALIDATED

      Source sequence(s)
      CU682811
      UniProtKB/TrEMBL
      A0A8M1RL59, F1R0Z8
      Conserved Domains (1) summary
      pfam01920
      Location:24 → 126
      Prefoldin_2; Prefoldin subunit

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      38151065..38160023 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002666519.6 → XP_002666565.1  prefoldin subunit 4

      UniProtKB/TrEMBL
      F1R0Z8
      Related
      ENSDARP00000081546.4, ENSDART00000087112.5
      Conserved Domains (1) summary
      pfam01920
      Location:24 → 126
      Prefoldin_2; Prefoldin subunit
    Nucleotide Protein Strain
    Heading Accession and Version

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