riok1 RIO kinase 1 (yeast) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: riok1provided by ZNC
Official Full Name: RIO kinase 1 (yeast)provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1927
See related: Ensembl:ENSDARG00000016399 AllianceGenome:ZFIN:ZDB-GENE-040426-1927
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb99f04; zgc:56195; wu:fb99f04
Summary: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to act upstream of or within phosphorylation and ribosome biogenesis. Predicted to be located in cytoplasm. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol. Orthologous to human RIOK1 (RIO kinase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (21063746..21076570)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (21405684..21418508)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb99f04.x1 (e-PCR)
- UniSTS:192014

fc89d02.y1 (e-PCR)
- UniSTS:194761

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in maturation of SSU-rRNA	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
part_of preribosome, small subunit precursor	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: serine/threonine-protein kinase RIO1

NP_998160.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212995.1 → NP_998160.1 serine/threonine-protein kinase RIO1

See identical proteins and their annotated locations for NP_998160.1

Status: PROVISIONAL

Source sequence(s)

BC045984

UniProtKB/TrEMBL

Q7ZV65

Related

ENSDARP00000022653.8, ENSDART00000022765.10

Conserved Domains (2) summary

COG1718
Location:144 → 383

RIO1; Serine/threonine-protein kinase RIO1 [Signal transduction mechanisms]

cd05147
Location:178 → 367

RIO1_euk; Catalytic domain of the atypical protein serine kinase, Eukaryotic RIO1 kinase