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    Zfp347 zinc finger protein 347 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 170902, updated on 8-May-2024

    Summary

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    Official Symbol
    Zfp347provided by RGD
    Official Full Name
    zinc finger protein 347provided by RGD
    Primary source
    RGD:620185
    See related
    Ensembl:ENSRNOG00000071023 AllianceGenome:RGD:620185
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Giot2
    Summary
    Orthologous to human ZNF14 (zinc finger protein 14). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 261.9), Heart (RPKM 36.6) and 9 other tissues See more
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    Genomic context

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    See Zfp347 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (8110793..8130161)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (7460543..7479378)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (9974310..9990960, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene serine and arginine rich splicing factor 7, pseudogene 7 Neighboring gene zinc finger protein 844 like, pseudogene 1 Neighboring gene zinc finger protein 844-like Neighboring gene zinc finger protein 938 Neighboring gene zinc finger protein 658B like, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cloning and characterization of gonadotropin-inducible ovarian transcription factors (GIOT1 and -2) that are novel members of the (Cys)(2)-(His)(2)-type zinc finger protein family. Mizutani T, et al. Mol Endocrinol, 2001 Oct. PMID 11579202
    2. The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis. Li ZZ, et al. Biosci Rep, 2020 Jan 31. PMID 31904090, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 347
    Names
    gonadotropin inducible ovarian transcription factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430215.1 → NP_001417144.1  zinc finger protein 347 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007

    2. NM_133390.2 → NP_596881.2  zinc finger protein 347 isoform 1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A6K849
      Conserved Domains (4) summary
      COG5048
      Location:339 → 699
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:372 → 392
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:180 → 198
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:273 → 298
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      8110793..8130161
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063262943.1 → XP_063119013.1  zinc finger protein 347 isoform X1

    2. XM_039078333.2 → XP_038934261.1  zinc finger protein 347 isoform X2

      Related
      ENSRNOP00000050722.4
      Conserved Domains (5) summary
      COG5048
      Location:371 → 731
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:404 → 424
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:212 → 230
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 44
      KRAB; KRAB box
      pfam13465
      Location:305 → 330
      zf-H2C2_2; Zinc-finger double domain

    3. XM_063262945.1 → XP_063119015.1  zinc finger protein 347 isoform X3

      UniProtKB/TrEMBL
      A6K849

    4. XM_063262944.1 → XP_063119014.1  zinc finger protein 347 isoform X3

      UniProtKB/TrEMBL
      A6K849

    5. XM_063262946.1 → XP_063119016.1  zinc finger protein 347 isoform X3

      UniProtKB/TrEMBL
      A6K849

    6. XM_039078337.2 → XP_038934265.1  zinc finger protein 347 isoform X4

      UniProtKB/TrEMBL
      A0A8I6GDJ0
      Related
      ENSRNOP00000094026.1
      Conserved Domains (4) summary
      COG5048
      Location:289 → 649
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:322 → 342
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:130 → 148
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:223 → 248
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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