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    Ntaq1 N-terminal glutamine amidase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362914, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Ntaq1provided by RGD
    Official Full Name
    N-terminal glutamine amidase 1provided by RGD
    Primary source
    RGD:1311362
    See related
    Ensembl:ENSRNOG00000006700 AllianceGenome:RGD:1311362
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Wdyhv1; RGD1311362
    Summary
    Predicted to enable protein-N-terminal glutamine amidohydrolase activity. Predicted to be involved in cellular protein modification process. Predicted to be active in cytosol and nucleus. Orthologous to human NTAQ1 (N-terminal glutamine amidase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 50.1), Muscle (RPKM 49.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ntaq1 in Genome Data Viewer
    Location:
    7q33
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (91573816..91593980)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (89684318..89704484)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (97957022..97977158, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S10, pseudogene 16 Neighboring gene ATPase family, AAA domain containing 2 Neighboring gene uncharacterized LOC134479909 Neighboring gene U7 small nuclear RNA Neighboring gene small nucleolar RNA, H/ACA box 11G Neighboring gene F-box protein 32 Neighboring gene uncharacterized LOC102549374

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Glutamine-specific N-terminal amidase, a component of the N-end rule pathway. Wang H, et al. Mol Cell, 2009 Jun 26. PMID 19560421, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109256

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein-N-terminal asparagine amidohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-N-terminal glutamine amidohydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-N-terminal glutamine amidohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-N-terminal glutamine amidohydrolase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein-N-terminal glutamine amidohydrolase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein modification process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein modification process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    protein N-terminal glutamine amidohydrolase
    Names
    N-terminal Gln amidase
    WDYHV motif containing 1
    WDYHV motif-containing protein 1
    nt(Q)-amidase
    protein NH2-terminal glutamine deamidase
    NP_001020195.1
    XP_017450434.1
    XP_038935446.1
    XP_038935447.1
    XP_063119914.1
    XP_063119915.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025024.2 → NP_001020195.1  protein N-terminal glutamine amidohydrolase

      See identical proteins and their annotated locations for NP_001020195.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      Q5BJV9
      UniProtKB/TrEMBL
      A6HRJ7, A6HRJ9
      Related
      ENSRNOP00000008785.6, ENSRNOT00000008785.7
      Conserved Domains (1) summary
      pfam09764
      Location:25 → 194
      Nt_Gln_amidase; N-terminal glutamine amidase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      91573816..91593980
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039079519.2 → XP_038935447.1  protein N-terminal glutamine amidohydrolase isoform X2

      Conserved Domains (1) summary
      pfam09764
      Location:25 → 115
      Nt_Gln_amidase; N-terminal glutamine amidase

    2. XM_063263845.1 → XP_063119915.1  protein N-terminal glutamine amidohydrolase isoform X3

    3. XM_063263844.1 → XP_063119914.1  protein N-terminal glutamine amidohydrolase isoform X3

    4. XM_039079518.2 → XP_038935446.1  protein N-terminal glutamine amidohydrolase isoform X1

      Conserved Domains (1) summary
      pfam09764
      Location:25 → 229
      Nt_Gln_amidase; N-terminal glutamine amidase

    5. XM_017594945.3 → XP_017450434.1  protein N-terminal glutamine amidohydrolase isoform X3

    RNA

    1. XR_010053005.1 RNA Sequence

    2. XR_010053004.1 RNA Sequence

    3. XR_005486667.2 RNA Sequence

    4. XR_010053006.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BJV9.1 GenPept UniProtKB/Swiss-Prot:Q5BJV9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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