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    Vsig2 V-set and immunoglobulin domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 57276, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Vsig2provided by MGI
    Official Full Name
    V-set and immunoglobulin domain containing 2provided by MGI
    Primary source
    MGI:MGI:1928009
    See related
    Ensembl:ENSMUSG00000001943 AllianceGenome:MGI:1928009
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CTX; Ctm; 1190004B15Rik; 2210413P10Rik
    Summary
    Predicted to be integral component of plasma membrane. Orthologous to human VSIG2 (V-set and immunoglobulin domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in stomach adult (RPKM 244.5), bladder adult (RPKM 48.8) and 3 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Vsig2 in Genome Data Viewer
    Location:
    9 A4; 9 20.78 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (37450551..37455501)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (37539255..37544205)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_23809 Neighboring gene Myb/SANT-like DNA-binding domain containing 2 Neighboring gene endothelial cell-specific adhesion molecule Neighboring gene STARR-seq mESC enhancer starr_23812 Neighboring gene neurogranin Neighboring gene predicted gene, 46107

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. CTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebrates. Chrétien I, et al. Eur J Immunol, 1998 Dec. PMID 9862345
    2. Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. Gu Z, et al. PLoS One, 2015. PMID 25826454, Free PMC Article
    3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC117653

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    V-set and immunoglobulin domain-containing protein 2
    Names
    CT-like protein
    CTM
    cortical thymocyte receptor (X. laevis CTX) like
    cortical thymocyte-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020518.2 → NP_065264.2  V-set and immunoglobulin domain-containing protein 2 precursor

      See identical proteins and their annotated locations for NP_065264.2

      Status: VALIDATED

      Source sequence(s)
      AC105958, AK008920, AV018710, BB869209
      Consensus CDS
      CCDS22980.1
      UniProtKB/Swiss-Prot
      Q9CVA4, Q9D0T4, Q9Z109
      Related
      ENSMUSP00000002008.6, ENSMUST00000002008.7
      Conserved Domains (3) summary
      smart00410
      Location:152 → 235
      IG_like; Immunoglobulin like
      pfam07686
      Location:32 → 143
      V-set; Immunoglobulin V-set domain
      cl11960
      Location:153 → 231
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      37450551..37455501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Z109.2 GenPept UniProtKB/Swiss-Prot:Q9Z109

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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