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    H2ac13 H2A clustered histone 13 [ Mus musculus (house mouse) ]

    Gene ID: 319191, updated on 11-Apr-2024

    Summary

    Official Symbol
    H2ac13provided by MGI
    Official Full Name
    H2A clustered histone 13provided by MGI
    Primary source
    MGI:MGI:2448457
    See related
    Ensembl:ENSMUSG00000071516 AllianceGenome:MGI:2448457
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H2a-291A; Hist1h2ai
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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    Genomic context

    See H2ac13 in Genome Data Viewer
    Location:
    13 A3.1; 13 7.93 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (21900582..21901029)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (21716412..21716859)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA methionine 7 (anticodon CAT) Neighboring gene STARR-positive B cell enhancer mm9_chr13:21808027-21808328 Neighboring gene H2B clustered histone 13 Neighboring gene STARR-positive B cell enhancer mm9_chr13:21809194-21809494 Neighboring gene H3 clustered histone 10 Neighboring gene STARR-positive B cell enhancer ABC_E261 Neighboring gene H2A clustered histone 14, pseudogene

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nucleosomal DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of CENP-A containing nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone H2A type 1-I
    Names
    Histone H2A type 1-I
    histone 1, H2ai
    histone 2, H2ai
    histone H2A type 1
    histone cluster 1, H2ai

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178182.2NP_835489.1  histone H2A type 1-I

      See identical proteins and their annotated locations for NP_835489.1

      Status: REVIEWED

      Source sequence(s)
      AL589651
      Consensus CDS
      CCDS26288.1
      UniProtKB/Swiss-Prot
      C0HKE1, C0HKE2, C0HKE3, C0HKE4, C0HKE5, C0HKE6, C0HKE7, C0HKE8, C0HKE9, P10812, P22752, Q149U0, Q5SZZ2
      UniProtKB/TrEMBL
      A0AUV1, B2RVF0
      Related
      ENSMUSP00000088285.3, ENSMUST00000070124.5
      Conserved Domains (1) summary
      PTZ00017
      Location:1130
      PTZ00017; histone H2A; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      21900582..21901029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)