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    Ceacam3 CEA cell adhesion molecule 3 [ Mus musculus (house mouse) ]

    Gene ID: 384557, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Ceacam3provided by MGI
    Official Full Name
    CEA cell adhesion molecule 3provided by MGI
    Primary source
    MGI:MGI:3646296
    See related
    Ensembl:ENSMUSG00000053228 AllianceGenome:MGI:3646296
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Psg24; cea12; EG384557
    Summary
    Orthologous to human CEACAM21 (CEA cell adhesion molecule 21). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward placenta adult (RPKM 81.1) See more
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    Genomic context

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    See Ceacam3 in Genome Data Viewer
    Location:
    7 A2; 7 9.15 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (16884122..16898891)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (17150197..17164966)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 45219 Neighboring gene pregnancy specific beta-1-glycoprotein 16 Neighboring gene ribosomal protein L15 pseudogene Neighboring gene pregnancy-specific beta-1-glycoprotein 29 Neighboring gene STARR-seq mESC enhancer starr_18153 Neighboring gene predicted gene, 42373 Neighboring gene predicted gene, 32772

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Structure and evolution of the mouse pregnancy-specific glycoprotein (Psg) gene locus. McLellan AS, et al. BMC Genomics, 2005 Jan 12. PMID 15647114, Free PMC Article
    2. Mouse pregnancy-specific glycoproteins: tissue-specific expression and evidence of association with maternal vasculature. Wynne F, et al. Reproduction, 2006 Apr. PMID 16595723
    3. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in T cell activation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    carcinoembryonic antigen-related cell adhesion molecule 3
    Names
    pregnancy-specific glycoprotein 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_054059.2 → NP_473400.1  carcinoembryonic antigen-related cell adhesion molecule 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC152074
      Consensus CDS
      CCDS57499.1
      UniProtKB/TrEMBL
      E9Q6J4
      Related
      ENSMUSP00000104131.3, ENSMUST00000108491.8
      Conserved Domains (3) summary
      cd05774
      Location:271 → 375
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00410
      Location:624 → 703
      IG_like; Immunoglobulin like
      cl11960
      Location:613 → 703
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      16884122..16898891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540149.4 → XP_006540212.1  carcinoembryonic antigen-related cell adhesion molecule 3 isoform X1

      Conserved Domains (2) summary
      cd05774
      Location:151 → 255
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:493 → 583
      Ig; Immunoglobulin domain

    2. XM_006540151.4 → XP_006540214.1  carcinoembryonic antigen-related cell adhesion molecule 3 isoform X3

      Conserved Domains (2) summary
      cd05774
      Location:151 → 255
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:271 → 316
      Ig; Immunoglobulin domain

    3. XM_006540150.4 → XP_006540213.1  carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2

      Conserved Domains (2) summary
      cd05774
      Location:197 → 301
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:303 → 393
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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