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    CG4630 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36458, updated on 10-May-2024

    Summary

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    Official Symbol
    CG4630provided by FlyBase
    Primary source
    FLYBASE:FBgn0033809
    Locus tag
    Dmel_CG4630
    See related
    AllianceGenome:FB:FBgn0033809
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4630
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG4630 in Genome Data Viewer
    Location:
    49F10-49F10; 2-68 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13215659..13219247, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9103164..9106752, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene FLICE-associated huge protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene aquaporin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene F-box synaptic protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In Vivo. Zhang P, et al. Int J Mol Sci, 2021 Dec 14. PMID 34948211, Free PMC Article
    2. Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters. Eraly SA, et al. Physiol Genomics, 2004 Jun 17. PMID 15054140
    3. Pri peptides are mediators of ecdysone for the temporal control of development. Chanut-Delalande H, et al. Nat Cell Biol, 2014 Nov. PMID 25344753
    4. Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. Engelhart DC, et al. Int J Mol Sci, 2020 Mar 15. PMID 32183456, Free PMC Article
    5. Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. Magwire MM, et al. PLoS Genet, 2010 Jul 29. PMID 20686706, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4630-PA
    CG4630-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13215659..13219247 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274019.1 → NP_001260948.1  uncharacterized protein Dmel_CG4630, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260948.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFK6
      Conserved Domains (2) summary
      cd06174
      Location:158 → 533
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:23 → 573
      2A0119; cation transport protein

    2. NM_137003.4 → NP_610847.3  uncharacterized protein Dmel_CG4630, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610847.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TW6
      Conserved Domains (2) summary
      cd06174
      Location:158 → 514
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:23 → 554
      2A0119; cation transport protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFK6 A0A0B4KFK6
    Q95TW6 Q95TW6

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