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    CG2818 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33597, updated on 10-May-2024

    Summary

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    Official Symbol
    CG2818provided by FlyBase
    Primary source
    FLYBASE:FBgn0031566
    Locus tag
    Dmel_CG2818
    See related
    AllianceGenome:FB:FBgn0031566
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2818
    Summary
    Predicted to enable glycerophosphocholine phosphodiesterase activity. Predicted to be involved in glycerophospholipid catabolic process. Is expressed in several structures, including ectoderm; hindgut anlage; and presumptive embryonic/larval system. Orthologous to human GPCPD1 (glycerophosphocholine phosphodiesterase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG2818 in Genome Data Viewer
    Location:
    24C1-24C1; 2-11 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3713360..3716810)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3713360..3716810)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene cutlet Neighboring gene uncharacterized protein Neighboring gene lectin-24A Neighboring gene Shaker cognate w Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
    2. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    3. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    4. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycerophosphocholine phosphodiesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables starch binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycerophospholipid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2818-PA
    CG2818-PB
    NP_608804.1
    NP_722936.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3713360..3716810
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134960.4 → NP_608804.1  uncharacterized protein Dmel_CG2818, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608804.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T074, Q9VQU3
      Related
      FBpp0077226
      Conserved Domains (3) summary
      cd05814
      Location:44 → 166
      CBM20_Prei4; Prei4, N-terminal CBM20 (carbohydrate-binding module, family 20) domain. Preimplantation protein 4 (Prei4) is a protein of unknown function that is expressed during mouse preimplantation embryogenesis. In addition to the N-terminal CBM20 domain, Prei4 ...
      cd08607
      Location:371 → 659
      GDPD_GDE5; Glycerophosphodiester phosphodiesterase domain of putative mammalian glycerophosphodiester phosphodiesterase GDE5 and similar proteins
      pfam03009
      Location:375 → 661
      GDPD; Glycerophosphoryl diester phosphodiesterase family

    2. NM_164553.2 → NP_722936.1  uncharacterized protein Dmel_CG2818, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722936.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQ03
      Related
      FBpp0077227
      Conserved Domains (2) summary
      cd08607
      Location:185 → 473
      GDPD_GDE5; Glycerophosphodiester phosphodiesterase domain of putative mammalian glycerophosphodiester phosphodiesterase GDE5 and similar proteins
      pfam03009
      Location:189 → 475
      GDPD; Glycerophosphoryl diester phosphodiesterase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQ03 Q8IQ03
    Q9VQU3 Q9VQU3

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