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    arpc3 actin related protein 2/3 complex, subunit 3 [ Danio rerio (zebrafish) ]

    Gene ID: 415204, updated on 27-Mar-2024

    Summary

    Official Symbol
    arpc3provided by ZNC
    Official Full Name
    actin related protein 2/3 complex, subunit 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-107
    See related
    Ensembl:ENSDARG00000057882 AllianceGenome:ZFIN:ZDB-GENE-040625-107
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:86828
    Summary
    Predicted to enable actin binding activity. Predicted to contribute to actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Predicted to act upstream of or within regulation of actin filament polymerization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of Arp2/3 protein complex. Orthologous to human ARPC3 (actin related protein 2/3 complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See arpc3 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (17024002..17029464)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (16987366..16992828)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene VPS29 retromer complex component Neighboring gene family with sequence similarity 216 member A Neighboring gene GPN-loop GTPase 3 Neighboring gene ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast) Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in Arp2/3 complex-mediated actin nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within Arp2/3 complex-mediated actin nucleation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of Arp2/3 protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Arp2/3 protein complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    actin-related protein 2/3 complex subunit 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002114.1NP_001002114.1  actin-related protein 2/3 complex subunit 3

      See identical proteins and their annotated locations for NP_001002114.1

      Status: PROVISIONAL

      Source sequence(s)
      AL844518
      UniProtKB/TrEMBL
      A8E5N5, Q6ZM62
      Related
      ENSDARP00000075074.5, ENSDART00000080628.6
      Conserved Domains (1) summary
      pfam04062
      Location:1173
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      17024002..17029464
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)