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    Gpr150 G protein-coupled receptor 150 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499486, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Gpr150provided by RGD
    Official Full Name
    G protein-coupled receptor 150provided by RGD
    Primary source
    RGD:1564729
    See related
    Ensembl:ENSRNOG00000026944 AllianceGenome:RGD:1564729
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564729
    Summary
    Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be integral component of plasma membrane. Orthologous to human GPR150 (G protein-coupled receptor 150). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 28.2), Spleen (RPKM 7.5) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gpr150 in Genome Data Viewer
    Location:
    2q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (7278166..7283216, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (5546304..5550889, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (2810280..2815991, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene Rho-related BTB domain containing 3 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene spermatogenesis associated 9 Neighboring gene Rieske (Fe-S) domain containing Neighboring gene arylsulfatase family, member K Neighboring gene SKI3 subunit of superkiller complex Neighboring gene small nucleolar RNA SNORA17 Neighboring gene family with sequence similarity 81, member B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular response to hormone stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable G-protein coupled receptor 150

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109173.1 → NP_001102643.1  probable G-protein coupled receptor 150

      See identical proteins and their annotated locations for NP_001102643.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473955
      UniProtKB/TrEMBL
      A6I4F7, D3ZHL8
      Related
      ENSRNOP00000037898.1, ENSRNOT00000029265.3
      Conserved Domains (1) summary
      pfam00001
      Location:66 → 345
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      7278166..7283216 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006231713.5 → XP_006231775.1  probable G-protein coupled receptor 150 isoform X1

      Conserved Domains (1) summary
      pfam00001
      Location:66 → 244
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    2. XM_039102822.2 → XP_038958750.1  probable G-protein coupled receptor 150 isoform X2

      Conserved Domains (2) summary
      cd14964
      Location:51 → 77
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:50 → 223
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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