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    tmem63ba transmembrane protein 63Ba [ Danio rerio (zebrafish) ]

    Gene ID: 100334023, updated on 27-Mar-2024

    Summary

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    Official Symbol
    tmem63baprovided by ZNC
    Official Full Name
    transmembrane protein 63Baprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4320
    See related
    Ensembl:ENSDARG00000104559 AllianceGenome:ZFIN:ZDB-GENE-030131-4320
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc90d11; tmem63b; wu:fc90d11
    Summary
    Predicted to enable calcium activated cation channel activity. Predicted to act upstream of or within ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human TMEM63B (transmembrane protein 63B). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See tmem63ba in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (46718690..46800473)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (46428864..46506818)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor receptor 2 Neighboring gene arginyltransferase 1 Neighboring gene coiled-coil domain-containing protein 177-like Neighboring gene zinc transporter ZIP9-B-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionary and Expression Analyses Show Co-option of khdrbs Genes for Origin of Vertebrate Brain. Wang S, et al. Front Genet, 2017. PMID 29354154, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium-activated cation channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium-activated cation channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 63B; CSC1-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      46718690..46800473
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480902.1 → XP_021336577.1  CSC1-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PYU1
      Conserved Domains (2) summary
      pfam14703
      Location:243 → 425
      PHM7_cyt; Cytosolic domain of 10TM putative phosphate transporter
      cl25971
      Location:2 → 438
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

    2. XM_005157065.4 → XP_005157122.1  CSC1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IKF9, A0A8M2B361
      Related
      ENSDARP00000134798.1, ENSDART00000160401.2
      Conserved Domains (4) summary
      pfam02714
      Location:365 → 707
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate
      pfam13967
      Location:117 → 224
      RSN1_TM; Late exocytosis, associated with Golgi transport
      pfam14703
      Location:277 → 346
      PHM7_cyt; Cytosolic domain of 10TM putative phosphate transporter
      cl10015
      Location:238 → 284
      YjgF_YER057c_UK114_family; YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no ...

    3. XM_002664229.6 → XP_002664275.2  CSC1-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A2R8S024, A0A8M1RHL6
      Related
      ENSDARP00000157107.1, ENSDART00000182884.1
      Conserved Domains (4) summary
      pfam02714
      Location:351 → 693
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate
      pfam13967
      Location:103 → 210
      RSN1_TM; Late exocytosis, associated with Golgi transport
      pfam14703
      Location:263 → 332
      PHM7_cyt; Cytosolic domain of 10TM putative phosphate transporter
      cl10015
      Location:224 → 270
      YjgF_YER057c_UK114_family; YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no ...

    4. XM_021480903.1 → XP_021336578.1  CSC1-like protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8M9QAG3
      Conserved Domains (1) summary
      cl25971
      Location:1 → 190
      RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate
    Nucleotide Protein Strain
    Heading Accession and Version

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