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    Spata24 spermatogenesis associated 24 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291676, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Spata24provided by RGD
    Official Full Name
    spermatogenesis associated 24provided by RGD
    Primary source
    RGD:1311742
    See related
    Ensembl:ENSRNOG00000019976 AllianceGenome:RGD:1311742
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311742
    Summary
    Predicted to enable DNA binding activity and identical protein binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human SPATA24 (spermatogenesis associated 24). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 854.1), Heart (RPKM 47.5) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Spata24 in Genome Data Viewer
    Location:
    18p11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (27523133..27531375, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (27249047..27257129, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (28446592..28454724, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene marginal zone B and B1 cell-specific protein Neighboring gene proline-rich basic protein 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C18 Neighboring gene endothelial cell surface expressed chemotaxis and apoptosis regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cloning and characterization of a novel spermiogenesis-related gene, T6441, in rat testis. Song XX, et al. Front Biosci, 2006 Jan 1. PMID 16146721
    2. TIPT, a male germ cell-specific partner of TRF2, is chromatin-associated and interacts with HP1. Brancorsini S, et al. Cell Cycle, 2008 May 15. PMID 18418073
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the T6441 gene may play a role in cytoplasm movement and removal during spermiogenesis
      Title: Cloning and characterization of a novel spermiogenesis-related gene, T6441, in rat testis.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in male germ cell nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    spermatogenesis-associated protein 24
    Names
    testis protein T6441

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025636.2 → NP_001020807.2  spermatogenesis-associated protein 24

      See identical proteins and their annotated locations for NP_001020807.2

      Status: VALIDATED

      Source sequence(s)
      BQ207964, CR463891, DQ080016
      UniProtKB/TrEMBL
      A6J2Z1
      Conserved Domains (1) summary
      pfam15175
      Location:25 → 128
      SPATA24; Spermatogenesis-associated protein 24

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      27523133..27531375 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006254545.5 → XP_006254607.1  spermatogenesis-associated protein 24 isoform X1

      See identical proteins and their annotated locations for XP_006254607.1

      UniProtKB/Swiss-Prot
      D3ZAG4, Q4PJT6
      Related
      ENSRNOP00000043703.2
      Conserved Domains (1) summary
      pfam15175
      Location:22 → 191
      SPATA24; Spermatogenesis-associated protein 24

    2. XM_039096723.2 → XP_038952651.1  spermatogenesis-associated protein 24 isoform X2

      Conserved Domains (1) summary
      pfam15175
      Location:22 → 128
      SPATA24; Spermatogenesis-associated protein 24
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4PJT6.3 GenPept UniProtKB/Swiss-Prot:Q4PJT6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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