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    dhrs7b dehydrogenase/reductase (SDR family) member 7B [ Danio rerio (zebrafish) ]

    Gene ID: 550454, updated on 27-Mar-2024

    Summary

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    Official Symbol
    dhrs7bprovided by ZNC
    Official Full Name
    dehydrogenase/reductase (SDR family) member 7Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-277
    See related
    Ensembl:ENSDARG00000075726 AllianceGenome:ZFIN:ZDB-GENE-050417-277
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:112518
    Summary
    Predicted to enable oxidoreductase activity, acting on CH-OH group of donors. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Orthologous to human DHRS7B (dehydrogenase/reductase 7B). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See dhrs7b in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (15847379..15859455, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (15699569..15709638, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene zgc:110779 Neighboring gene transmembrane protein 11 Neighboring gene cramped chromatin regulator homolog 1 Neighboring gene Jupiter microtubule associated homolog 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood. Weeks O, et al. J Clin Invest, 2020 May 1. PMID 32202514, Free PMC Article
    2. Insights Into the Peroxisomal Protein Inventory of Zebrafish. Kamoshita M, et al. Front Physiol, 2022. PMID 35295584, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on CH-OH group of donors IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dehydrogenase/reductase SDR family member 7B
    Names
    short-chain dehydrogenase/reductase family 32C member 1
    NP_001017758.1
    XP_021326304.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017758.1 → NP_001017758.1  dehydrogenase/reductase SDR family member 7B

      See identical proteins and their annotated locations for NP_001017758.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093357
      UniProtKB/Swiss-Prot
      Q566S6
      Conserved Domains (2) summary
      cd05332
      Location:35 → 296
      11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs
      PRK06181
      Location:37 → 302
      PRK06181; short chain dehydrogenase; Provisional

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      15847379..15859455 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470629.1 → XP_021326304.1  dehydrogenase/reductase SDR family member 7B isoform X1

      UniProtKB/TrEMBL
      A0A8M9PN38, F1QWU6
      Related
      ENSDARP00000122514.1, ENSDART00000135924.2
      Conserved Domains (1) summary
      cd05332
      Location:42 → 303
      11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q566S6.1 GenPept UniProtKB/Swiss-Prot:Q566S6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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