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    ubr7 ubiquitin protein ligase E3 component n-recognin 7 [ Danio rerio (zebrafish) ]

    Gene ID: 322815, updated on 27-Mar-2024

    Summary

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    Official Symbol
    ubr7provided by ZNC
    Official Full Name
    ubiquitin protein ligase E3 component n-recognin 7provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-1535
    See related
    Ensembl:ENSDARG00000005536 AllianceGenome:ZFIN:ZDB-GENE-030131-1535
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb74a06; zgc:55404; wu:fb74a06; wu:fi29b06
    Summary
    Predicted to enable ligase activity; ubiquitin protein ligase activity; and zinc ion binding activity. Orthologous to human UBR7 (ubiquitin protein ligase E3 component n-recognin 7). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See ubr7 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (27092665..27107703)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (27193987..27208613)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene si:dkeyp-55f12.3 Neighboring gene transmembrane protein 251 Neighboring gene BTB (POZ) domain containing 7 Neighboring gene si:dkey-85n7.8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Positive correlation between gene coexpression and positional clustering in the zebrafish genome. Ng YK, et al. BMC Genomics, 2009 Jan 22. PMID 19159490, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative E3 ubiquitin-protein ligase UBR7
    NP_997794.1
    XP_021324040.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212629.1 → NP_997794.1  putative E3 ubiquitin-protein ligase UBR7

      See identical proteins and their annotated locations for NP_997794.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044390
      UniProtKB/TrEMBL
      Q803P8
      Related
      ENSDARP00000019360.2, ENSDART00000024595.5
      Conserved Domains (2) summary
      cd15542
      Location:127 → 178
      PHD_UBR7; PHD finger found in putative E3 ubiquitin-protein ligase UBR7
      pfam02207
      Location:49 → 106
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      27092665..27107703
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021468365.1 → XP_021324040.1  putative E3 ubiquitin-protein ligase UBR7 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PSI6
      Conserved Domains (2) summary
      cd15542
      Location:127 → 178
      PHD_UBR7; PHD finger found in putative E3 ubiquitin-protein ligase UBR7
      pfam02207
      Location:49 → 106
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
    Nucleotide Protein Strain
    Heading Accession and Version

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