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    TP53I11 tumor protein p53 inducible protein 11 [ Homo sapiens (human) ]

    Gene ID: 9537, updated on 6-Jun-2024

    Summary

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    Official Symbol
    TP53I11provided by HGNC
    Official Full Name
    tumor protein p53 inducible protein 11provided by HGNC
    Primary source
    HGNC:HGNC:16842
    See related
    Ensembl:ENSG00000175274 MIM:617867; AllianceGenome:HGNC:16842
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PIG11
    Summary
    Predicted to be involved in negative regulation of cell population proliferation. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in lung (RPKM 12.0), fat (RPKM 11.2) and 25 other tissues See more
    Orthologs
    mouse all
    NEW
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    Genomic context

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    See TP53I11 in Genome Data Viewer
    Location:
    11p11.2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (44932348..44951306, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (45089188..45108296, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (44953899..44972857, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:44710524-44711057 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44713680-44714180 Neighboring gene long intergenic non-protein coding RNA 2704 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:44729901-44731100 Neighboring gene Sharpr-MPRA regulatory region 8672 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44747040-44747900 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44747901-44748762 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3279 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:44750014-44750516 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:44750517-44751017 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44763637-44764332 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44764333-44765028 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44770929-44771430 Neighboring gene tetraspanin 18 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44774444-44775252 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44775253-44776059 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44787811-44788311 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44795688-44796462 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44798427-44798928 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44798929-44799428 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21411 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44806959-44807560 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44807561-44808160 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44816852-44817768 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:44819455-44820133 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21423 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44844210-44845075 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44845076-44845940 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44845941-44846806 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21436 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21440 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21441 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21442 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44869391-44869986 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44870581-44871176 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44871177-44871770 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21450 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44878622-44879400 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44883049-44883676 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44883677-44884304 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4663 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44907116-44907616 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44907617-44908117 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44914725-44915296 Neighboring gene uncharacterized LOC124902664 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44932558-44933414 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4664 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44944349-44944850 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44952242-44952850 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44957874-44958474 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44960045-44960758 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44964865-44965513 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44966723-44967326 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3281 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3282 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44985644-44986316 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44986317-44986988 Neighboring gene uncharacterized LOC105376649 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44996027-44996672 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44997901-44998858 Neighboring gene long intergenic non-protein coding RNA 2685 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:45011181-45012070 Neighboring gene uncharacterized LOC105376650 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:45062883-45063384

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. TP53I11 suppresses epithelial-mesenchymal transition and metastasis of breast cancer cells. Xiao T, et al. BMB Rep, 2019 Jun. PMID 30940320, Free PMC Article
    2. PIG11 is involved in hepatocellular carcinogenesis and its over-expression promotes Hepg2 cell apoptosis. Wu Y, et al. Pathol Oncol Res, 2009 Sep. PMID 19096915
    3. PIG11 protein binds to DNA in sequence-independent manner in vitro. Xiong XF, et al. Biochem Biophys Res Commun, 2007 Jun 22. PMID 17482569
    4. Jasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cells. Fingrut O, et al. Br J Pharmacol, 2005 Nov. PMID 16170329, Free PMC Article
    5. A P53 target gene, PIG11, contributes to chemosensitivity of cells to arsenic trioxide. Liang XQ, et al. FEBS Lett, 2004 Jul 2. PMID 15225615

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells <em>via</em> regulation of miR-1234/TP53I11 axis.
      Title: Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells <em>via</em> regulation of miR-1234/TP53I11 axis.
    2. MiR-645 promotes proliferation and migration of non-small cell lung cancer cells by targeting TP53I11.
      Title: MiR-645 promotes proliferation and migration of non-small cell lung cancer cells by targeting TP53I11.
    3. TP53I11 functions as a mediator to balance activation of AKT and AMPK to adapt cells to different cellular contexts such as extracellular matrix-attachment and -detachment.
      Title: Loss of TP53I11 Enhances the Extracellular Matrix-independent Survival by Promoting Activation of AMPK.
    4. Findings showed that hypoxic treatment upregulated the expression of HIF1alpha, but reduced TP53I11 protein levels and TP53I11 overexpression reduced HIF1alpha expression under normal culture and hypoxicconditions, and in xenografts of MDA-MB-231 cells.
      Title: TP53I11 suppresses epithelial-mesenchymal transition and metastasis of breast cancer cells.
    5. PIG11 is considered to be a new candidate liver tumour suppressor gene.
      Title: PIG11 is involved in hepatocellular carcinogenesis and its over-expression promotes Hepg2 cell apoptosis.
    6. Jasmonates can circumvent drug resistance induced by p53 mutations.
      Title: Jasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cells.
    7. Overexpression of PIG11 could induce cell apoptosis in the low levels and enhanced the apoptotic effects of arsenic trioxide
      Title: A P53 target gene, PIG11, contributes to chemosensitivity of cells to arsenic trioxide.
    8. PIG11 protein may play an important role by interaction with other biological molecules in the regulation of apoptosis and provided us a novel angel of view to explore the possible function of PIG11 in vivo.
      Title: PIG11 protein binds to DNA in sequence-independent manner in vitro.
    9. PIG11, as a downstream target of p53, is involved in apoptosis of gastric cancer cells
      Title: P53-induced gene 11 (PIG11) involved in arsenic trioxide-induced apoptosis in human gastric cancer MGC-803 cells.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in negative regulation of cell population proliferation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tumor protein p53-inducible protein 11
    Names
    p53-induced gene 11 protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001258320.2 → NP_001245249.1  tumor protein p53-inducible protein 11 isoform a

      See identical proteins and their annotated locations for NP_001245249.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 all encode the same isoform (a).
      Source sequence(s)
      AC068858, AC092733
      Consensus CDS
      CCDS7911.1
      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Related
      ENSP00000436152.1, ENST00000533940.5
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    2. NM_001258321.1 → NP_001245250.1  tumor protein p53-inducible protein 11 isoform a

      See identical proteins and their annotated locations for NP_001245250.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 all encode the same isoform (a).
      Source sequence(s)
      AC092733, AK054815, DA190266, DA697978
      Consensus CDS
      CCDS7911.1
      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Related
      ENSP00000309532.5, ENST00000308212.9
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    3. NM_001258322.1 → NP_001245251.1  tumor protein p53-inducible protein 11 isoform a

      See identical proteins and their annotated locations for NP_001245251.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 all encode the same isoform (a).
      Source sequence(s)
      AC092733, AK054815, DA115495, DA190266
      Consensus CDS
      CCDS7911.1
      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    4. NM_001258323.3 → NP_001245252.1  tumor protein p53-inducible protein 11 isoform a

      See identical proteins and their annotated locations for NP_001245252.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 all encode the same isoform (a).
      Source sequence(s)
      AC068858, AC092733
      Consensus CDS
      CCDS7911.1
      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Related
      ENSP00000379009.3, ENST00000395648.7
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    5. NM_001258324.1 → NP_001245253.1  tumor protein p53-inducible protein 11 isoform a

      See identical proteins and their annotated locations for NP_001245253.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 all encode the same isoform (a).
      Source sequence(s)
      AC092733, AK054815, AL537510, DA190266
      Consensus CDS
      CCDS7911.1
      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Related
      ENSP00000481456.1, ENST00000616990.4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    6. NM_001318384.2 → NP_001305313.1  tumor protein p53-inducible protein 11 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 all encode the same isoform (a).
      Source sequence(s)
      AC068858, AC092733
      Consensus CDS
      CCDS7911.1
      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    7. NM_001318385.1 → NP_001305314.1  tumor protein p53-inducible protein 11 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 all encode the same isoform (a).
      Source sequence(s)
      AC092733, AK056379, DA190266, DA778197, HY350915
      Consensus CDS
      CCDS7911.1
      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    8. NM_001318386.1 → NP_001305315.1  tumor protein p53-inducible protein 11 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 all encode the same isoform (a).
      Source sequence(s)
      AC092733, AK056379, DA190266, DA410127, HY350915
      Consensus CDS
      CCDS7911.1
      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    9. NM_001318387.2 → NP_001305316.1  tumor protein p53-inducible protein 11 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) differs in the 5' UTR and lacks two alternate coding exons compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter and has a different internal segment compared to isoform a.
      Source sequence(s)
      AC068858, AC092733
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 136
      p53-inducible11; Tumour protein p53-inducible protein 11

    10. NM_001318388.2 → NP_001305317.1  tumor protein p53-inducible protein 11 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11) differs in the 5' UTR and lacks an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (c) has a shorter and distinct N-terminus compared to isoform a.
      Source sequence(s)
      AC068858, AC092733
      UniProtKB/TrEMBL
      Q8N8U5
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 135
      p53-inducible11; Tumour protein p53-inducible protein 11

    11. NM_001318389.2 → NP_001305318.1  tumor protein p53-inducible protein 11 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12) differs in the 5' UTR and lacks an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (d) has a shorter and distinct N-terminus compared to isoform a.
      Source sequence(s)
      AC068858, AC092733
      Conserved Domains (1) summary
      pfam14936
      Location:34 → 113
      p53-inducible11; tumor protein p53-inducible protein 11

    12. NM_001318390.2 → NP_001305319.1  tumor protein p53-inducible protein 11 isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13) differs in the 5' UTR and uses an alternate splice junction in the coding region compared to variant 1, that causes a frameshift. The resulting isoform (e) has a shorter and distinct N-terminus compared to isoform a.
      Source sequence(s)
      AC068858, AC092733
      Conserved Domains (1) summary
      pfam14936
      Location:1 → 110
      p53-inducible11; Tumour protein p53-inducible protein 11

    13. NM_006034.5 → NP_006025.2  tumor protein p53-inducible protein 11 isoform a

      See identical proteins and their annotated locations for NP_006025.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 all encode the same isoform (a).
      Source sequence(s)
      AC068858, AC092733
      Consensus CDS
      CCDS7911.1
      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Related
      ENSP00000433474.1, ENST00000525680.6
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    RNA

    1. NR_134612.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14) differs in the 5' UTR and contains an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC068858, AC092733

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      44932348..44951306 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047427893.1 → XP_047283849.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    2. XM_011520478.2 → XP_011518780.1  tumor protein p53-inducible protein 11 isoform X1

      See identical proteins and their annotated locations for XP_011518780.1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Related
      ENSP00000433454.1, ENST00000528473.5
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    3. XM_005253227.4 → XP_005253284.1  tumor protein p53-inducible protein 11 isoform X1

      See identical proteins and their annotated locations for XP_005253284.1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    4. XM_011520477.2 → XP_011518779.1  tumor protein p53-inducible protein 11 isoform X1

      See identical proteins and their annotated locations for XP_011518779.1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    5. XM_017018581.2 → XP_016874070.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    6. XM_011520476.3 → XP_011518778.1  tumor protein p53-inducible protein 11 isoform X1

      See identical proteins and their annotated locations for XP_011518778.1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    7. XM_047427892.1 → XP_047283848.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    8. XM_017018580.3 → XP_016874069.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 188
      p53-inducible11; tumor protein p53-inducible protein 11

    9. XM_047427891.1 → XP_047283847.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    10. XM_047427890.1 → XP_047283846.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    11. XM_047427894.1 → XP_047283850.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/TrEMBL
      U3KQ32

    12. XM_005253229.2 → XP_005253286.1  tumor protein p53-inducible protein 11 isoform X2

      See identical proteins and their annotated locations for XP_005253286.1

      UniProtKB/TrEMBL
      U3KQ32
      Related
      ENSP00000475501.1, ENST00000531928.6
      Conserved Domains (1) summary
      pfam14936
      Location:10 → 114
      p53-inducible11; Tumour protein p53-inducible protein 11

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      45089188..45108296 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054370550.1 → XP_054226525.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    2. XM_054370554.1 → XP_054226529.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    3. XM_054370552.1 → XP_054226527.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    4. XM_054370551.1 → XP_054226526.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    5. XM_054370544.1 → XP_054226519.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    6. XM_054370545.1 → XP_054226520.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    7. XM_054370549.1 → XP_054226524.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    8. XM_054370553.1 → XP_054226528.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    9. XM_054370546.1 → XP_054226521.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    10. XM_054370548.1 → XP_054226523.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    11. XM_054370547.1 → XP_054226522.1  tumor protein p53-inducible protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O14683, Q3ZCS0
      UniProtKB/TrEMBL
      E9PKZ4

    12. XM_054370556.1 → XP_054226531.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/TrEMBL
      U3KQ32

    13. XM_054370555.1 → XP_054226530.1  tumor protein p53-inducible protein 11 isoform X2

      UniProtKB/TrEMBL
      U3KQ32

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001076787.1: Suppressed sequence

      Description
      NM_001076787.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O14683.2 GenPept UniProtKB/Swiss-Prot:O14683

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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