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    dnaja3a DnaJ heat shock protein family (Hsp40) member A3a [ Danio rerio (zebrafish) ]

    Gene ID: 335894, updated on 27-Mar-2024

    Summary

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    Official Symbol
    dnaja3aprovided by ZNC
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member A3aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7837
    See related
    Ensembl:ENSDARG00000058494 AllianceGenome:ZFIN:ZDB-GENE-030131-7837
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fj36c02
    Summary
    Predicted to enable protein kinase binding activity. Predicted to be involved in mitochondrion organization and negative regulation of apoptotic process. Predicted to act upstream of or within protein folding and response to heat. Predicted to be active in mitochondrion. Orthologous to human DNAJA3 (DnaJ heat shock protein family (Hsp40) member A3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See dnaja3a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (11926062..11947672)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (11985831..12007472)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene dynein heavy chain-like Neighboring gene forkhead box K2b Neighboring gene heme oxygenase 2b Neighboring gene cilia and flagella associated protein 70

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Selection of reliable biomarkers from PCR array analyses using relative distance computational model: methodology and proof-of-concept study. Liu C, et al. PLoS One, 2013. PMID 24349563, Free PMC Article
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heat shock protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to heat IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DnaJ heat shock protein family (Hsp40) member A3a; dnaJ homolog subfamily A member 3, mitochondrial
    Names
    DnaJ (Hsp40) homolog, subfamily A, member 3A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201313.1 → NP_958470.1  DnaJ heat shock protein family (Hsp40) member A3a

      See identical proteins and their annotated locations for NP_958470.1

      Status: PROVISIONAL

      Source sequence(s)
      BC047809
      UniProtKB/TrEMBL
      B2GT20, Q7ZUW0
      Related
      ENSDARP00000075810.4, ENSDART00000081367.5
      Conserved Domains (4) summary
      cd10719
      Location:236 → 296
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
      cd10747
      Location:207 → 416
      DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
      COG0484
      Location:89 → 435
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      pfam00226
      Location:91 → 153
      DnaJ; DnaJ domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      11926062..11947672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005168471.4 → XP_005168528.1  dnaJ homolog subfamily A member 3, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8M2BFS1
      Conserved Domains (4) summary
      cd10719
      Location:236 → 296
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
      cd10747
      Location:207 → 416
      DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
      COG0484
      Location:89 → 474
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      pfam00226
      Location:91 → 153
      DnaJ; DnaJ domain

    RNA

    1. XR_224326.4 RNA Sequence

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394520.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      59528..81094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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