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    mrpl2 mitochondrial ribosomal protein L2 [ Danio rerio (zebrafish) ]

    Gene ID: 571648, updated on 27-Mar-2024

    Summary

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    Official Symbol
    mrpl2provided by ZNC
    Official Full Name
    mitochondrial ribosomal protein L2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050809-12
    See related
    Ensembl:ENSDARG00000062568 AllianceGenome:ZFIN:ZDB-GENE-050809-12
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:6908224
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to act upstream of or within translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in visceral fat. Orthologous to human MRPL2 (mitochondrial ribosomal protein L2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See mrpl2 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (51877841..51903165, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (51653169..51662971, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene type I inositol 1,4,5-trisphosphate 5-phosphatase Neighboring gene PWWP domain containing 2B Neighboring gene zmp:0000000755 Neighboring gene LBH regulator of WNT signaling pathway Neighboring gene serum response factor b Neighboring gene kinesin light chain 1b Neighboring gene protein tyrosine kinase 7b Neighboring gene lysocardiolipin acyltransferase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Why does the zebrafish cloche mutant develop lens cataract? Posner M, et al. PLoS One, 2019. PMID 30861003, Free PMC Article
    2. Fatty Acid Oxidation in Zebrafish Adipose Tissue Is Promoted by 1α,25(OH)(2)D(3). Peng X, et al. Cell Rep, 2017 May 16. PMID 28514663
    3. Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification. Reischauer S, et al. Nature, 2016 Jul 14. PMID 27411634
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    39S ribosomal protein L2, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001327785.1 → NP_001314714.1  39S ribosomal protein L2, mitochondrial precursor

      Status: VALIDATED

      Source sequence(s)
      EH543927, EH565060, LT631685
      UniProtKB/TrEMBL
      A0A8M1P304, E7F8R3
      Related
      ENSDARP00000085077.4, ENSDART00000090644.6
      Conserved Domains (1) summary
      cl27214
      Location:53 → 260
      Ribosomal_L2_C; Ribosomal Proteins L2, C-terminal domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      51877841..51903165 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480651.1 → XP_021336326.1  39S ribosomal protein L2, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8M1P304, E7F8R3
      Conserved Domains (1) summary
      cl27214
      Location:53 → 260
      Ribosomal_L2_C; Ribosomal Proteins L2, C-terminal domain

    2. XM_021480652.1 → XP_021336327.1  39S ribosomal protein L2, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A8M1P304, E7F8R3
      Conserved Domains (1) summary
      cl27214
      Location:53 → 260
      Ribosomal_L2_C; Ribosomal Proteins L2, C-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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