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    ckap2l cytoskeleton associated protein 2-like [ Danio rerio (zebrafish) ]

    Gene ID: 569937, updated on 27-Mar-2024

    Summary

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    Official Symbol
    ckap2lprovided by ZNC
    Official Full Name
    cytoskeleton associated protein 2-likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6690
    See related
    Ensembl:ENSDARG00000100573 AllianceGenome:ZFIN:ZDB-GENE-030131-6690
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fa02g08; wu:fa02g08; si:ch211-230g14.4; si:ch211-255a21.1
    Summary
    Predicted to be located in cytoplasm. Predicted to be active in centrosome; cytosol; and mitotic spindle. Human ortholog(s) of this gene implicated in Filippi syndrome. Orthologous to human CKAP2L (cytoskeleton associated protein 2 like). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See ckap2l in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (13549608..13561069)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (13049391..13060852)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene SEC14-like lipid binding 8 Neighboring gene novel protein similar to human and mouse cyclin M4 (CNNM4) Neighboring gene uncharacterized LOC101885304 Neighboring gene si:ch211-230g14.3 Neighboring gene uncharacterized LOC101885516

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes. Gui H, et al. Genome Biol, 2017 Mar 8. PMID 28274275, Free PMC Article
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitotic spindle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cytoskeleton-associated protein 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001126431.2 → NP_001119903.2  cytoskeleton-associated protein 2-like

      Status: VALIDATED

      Source sequence(s)
      AL954191
      UniProtKB/TrEMBL
      A2BG40
      Related
      ENSDARP00000139380.1, ENSDART00000171270.2
      Conserved Domains (1) summary
      pfam15297
      Location:446 → 761
      CKAP2_C; Cytoskeleton-associated protein 2 C-terminus

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      13549608..13561069
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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