ccl19a.1 chemokine (C-C motif) ligand 19a, tandem duplicate 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ccl19a.1provided by ZNC
Official Full Name: chemokine (C-C motif) ligand 19a, tandem duplicate 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-060526-181
See related: Ensembl:ENSDARG00000058389 AllianceGenome:ZFIN:ZDB-GENE-060526-181
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ccl-c5a; si:ch211-89f7.4
Summary: Predicted to enable CCR chemokine receptor binding activity and chemokine activity. Acts upstream of or within dorsal/ventral pattern formation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human CCL19 (C-C motif chemokine ligand 19). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (13353860..13392579)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (12853643..12892362)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables CCR chemokine receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables chemokine activity	IBA Inferred from Biological aspect of Ancestor more info
enables chemokine activity	IEA Inferred from Electronic Annotation more info
enables cytokine activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell chemotaxis	IBA Inferred from Biological aspect of Ancestor more info
involved_in chemokine-mediated signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within chemotaxis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within dorsal/ventral pattern formation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within dorsal/ventral pattern formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within immune response	IEA Inferred from Electronic Annotation more info
involved_in inflammatory response	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cell migration	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: C-C motif chemokine 19a.1; chemokine (C-C motif) ligand 19a, tandem duplicate 1

Names: CCL-chr5a; CCL19aa; chemokine CCL-C5a

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001082906.2 → NP_001076375.2 C-C motif chemokine 19a.1 precursor

See identical proteins and their annotated locations for NP_001076375.2

Status: PROVISIONAL

Source sequence(s)

AB331770

UniProtKB/TrEMBL

A9ZPF5

Related

ENSDARP00000156538.1, ENSDART00000191190.1

Conserved Domains (1) summary

pfam00048
Location:34 → 91

IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

13353860..13392579

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005165054.1 → XP_005165111.1 chemokine (C-C motif) ligand 19a, tandem duplicate 1 isoform X1

UniProtKB/TrEMBL

A0A8M2BCA0, A2BIR2

Related

ENSDARP00000090385.3, ENSDART00000099611.4

Conserved Domains (1) summary

pfam00048
Location:34 → 91

IL8; Small cytokines (intecrine/chemokine), interleukin-8 like