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    gdf7 growth differentiation factor 7 [ Danio rerio (zebrafish) ]

    Gene ID: 30642, updated on 27-Mar-2024

    Summary

    Official Symbol
    gdf7provided by ZNC
    Official Full Name
    growth differentiation factor 7provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-990714-1
    See related
    Ensembl:ENSDARG00000042784 AllianceGenome:ZFIN:ZDB-GENE-990714-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    bmp12
    Summary
    Predicted to enable cytokine activity. Predicted to be involved in BMP signaling pathway; SMAD protein signal transduction; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; cardiovascular system; liver; muscle; and pleuroperitoneal region. Orthologous to human GDF7 (growth differentiation factor 7). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See gdf7 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (30833347..30840643, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (30817856..30822766, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene apolipoprotein Ba Neighboring gene lipid droplet associated hydrolase Neighboring gene tripeptidyl peptidase I Neighboring gene YY1 transcription factor a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cytokine activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    growth differentiation factor 7; growth/differentiation factor 6-A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      30833347..30840643 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_689471.6XP_694563.2  growth/differentiation factor 6-A

      UniProtKB/TrEMBL
      A0A8N7TFB7
      Related
      ENSDARP00000118202.1, ENSDART00000139707.2
      Conserved Domains (2) summary
      smart00204
      Location:324422
      TGFB; Transforming growth factor-beta (TGF-beta) family
      pfam00688
      Location:62250
      TGFb_propeptide; TGF-beta propeptide