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    slc25a11 solute carrier family 25 member 11 [ Danio rerio (zebrafish) ]

    Gene ID: 415189, updated on 25-Apr-2024

    Summary

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    Official Symbol
    slc25a11provided by ZNC
    Official Full Name
    solute carrier family 25 member 11provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-79
    See related
    Ensembl:ENSDARG00000035741 AllianceGenome:ZFIN:ZDB-GENE-040625-79
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fa07h09; zgc:86898; wu:fa07h09
    Summary
    Predicted to enable C4-dicarboxylate transmembrane transporter activity; antiporter activity; and sulfur compound transmembrane transporter activity. Predicted to be involved in anion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in paraganglioma. Orthologous to human SLC25A11 (solute carrier family 25 member 11). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See slc25a11 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (68076913..68093169, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (67397951..67414207, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 167 Neighboring gene sperm associated antigen 7 Neighboring gene voltage-gated potassium channel subunit beta-2-like Neighboring gene kinesin family member 1C, a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Structures, evolutionary relationships and expression profiles of the tumour necrosis factor superfamily and their receptors in black rockfish (Sebastes schlegelii). Cao M, et al. Dev Comp Immunol, 2022 Jul. PMID 35364135
    2. Hepatic gene expression profiling using GeneChips in zebrafish exposed to 17alpha-methyldihydrotestosterone. Hoffmann JL, et al. Aquat Toxicol, 2008 Apr 28. PMID 18339436
    3. Expression and regulation of drug transporters in vertebrate neutrophils. Foulkes MJ, et al. Sci Rep, 2017 Jul 10. PMID 28694436, Free PMC Article
    4. Understanding the complexity of epimorphic regeneration in zebrafish caudal fin tissue: A transcriptomic and proteomic approach. Banu S, et al. Genomics, 2022 Mar. PMID 35134499
    5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables malate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxaloacetate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables succinate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables thiosulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in malate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in oxaloacetate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphate ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in succinate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in thiosulfate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 2-oxoglutarate/malate carrier protein
    Names
    solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002099.1 → NP_001002099.1  mitochondrial 2-oxoglutarate/malate carrier protein

      See identical proteins and their annotated locations for NP_001002099.1

      Status: PROVISIONAL

      Source sequence(s)
      BC071521
      UniProtKB/TrEMBL
      Q6IQ89
      Related
      ENSDARP00000051848.3, ENSDART00000051849.4
      Conserved Domains (2) summary
      PTZ00169
      Location:19 → 300
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:213 → 305
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      68076913..68093169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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