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    pacrg PARK2 co-regulated [ Danio rerio (zebrafish) ]

    Gene ID: 492757, updated on 27-Mar-2024

    Summary

    Official Symbol
    pacrgprovided by ZNC
    Official Full Name
    PARK2 co-regulatedprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041114-100
    See related
    Ensembl:ENSDARG00000087556 AllianceGenome:ZFIN:ZDB-GENE-041114-100
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:101786
    Summary
    Predicted to enable Hsp70 protein binding activity; Hsp90 protein binding activity; and chaperone binding activity. Acts upstream of or within determination of left/right symmetry. Predicted to be active in cytosol; neuron projection; and vesicle. Is expressed in several structures, including Kupffer's vesicle; axis; forerunner cell group; nervous system; and pronephros. Orthologous to human PACRG (parkin coregulated). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See pacrg in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (27545214..27706746)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (27528251..27689783)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene vestigial-like family member 2b Neighboring gene cathepsin L.1 Neighboring gene QKI, KH domain containing, RNA binding a Neighboring gene platelet-activating factor receptor

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables Hsp70 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables Hsp90 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within determination of left/right symmetry IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    parkin coregulated gene protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007398.2NP_001007399.1  parkin coregulated gene protein

      See identical proteins and their annotated locations for NP_001007399.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085440
      UniProtKB/TrEMBL
      Q5U3Q1
      Related
      ENSDARP00000106202.2, ENSDART00000129392.3
      Conserved Domains (1) summary
      pfam10274
      Location:45228
      ParcG; Parkin co-regulated protein

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      27545214..27706746
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)