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    loaf lost and found [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39325, updated on 10-May-2024

    Summary

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    Official Symbol
    loafprovided by FlyBase
    Official Full Name
    lost and foundprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036202
    Locus tag
    Dmel_CG6024
    See related
    AllianceGenome:FB:FBgn0036202
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6024; CT18912; Dmel\CG6024
    Summary
    Located in cytoplasm. Is expressed in adult head; embryonic brain; embryonic/larval nervous system; larval ventral nerve cord; and organism. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See loaf in Genome Data Viewer
    Location:
    68D3-68D4; 3-36 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11733589..11766182, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11726689..11759282, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene bmcp Neighboring gene sisters unbound Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 68a Neighboring gene Mucin 68D Neighboring gene mir-314 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. R7 photoreceptor axon targeting depends on the relative levels of lost and found expression in R7 and its synaptic partners. Douthit J, et al. Elife, 2021 May 18. PMID 34003117, Free PMC Article
    2. Differential activation of JAK-STAT signaling reveals functional compartmentalization in Drosophila blood progenitors. Rodrigues D, et al. Elife, 2021 Feb 17. PMID 33594977, Free PMC Article
    3. RNA polymerase II kinetics in polo polyadenylation signal selection. Pinto PA, et al. EMBO J, 2011 May 20. PMID 21602789, Free PMC Article
    4. A Cyclin E Centered Genetic Network Contributes to Alcohol-Induced Variation in Drosophila Development. Morozova TV, et al. G3 (Bethesda), 2018 Jul 31. PMID 29871898, Free PMC Article
    5. Systematic identification of genes regulating synaptic remodeling in the Drosophila visual system. Araki T, et al. Genes Genet Syst, 2020 Aug 27. PMID 32493879

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    acts_upstream_of synaptic target recognition IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lost and found
    Names
    CG6024-PC
    CG6024-PF
    CG6024-PG
    loaf-PC
    loaf-PF
    loaf-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11733589..11766182 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104119.2 → NP_001097589.2  lost and found, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097589.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BIG2
      Conserved Domains (2) summary
      smart00192
      Location:216 → 247
      LDLa; Low-density lipoprotein receptor domain class A
      cl00049
      Location:121 → 209
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

    2. NM_001382185.1 → NP_001368949.1  lost and found, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A6J3SW69
      Conserved Domains (1) summary
      smart00192
      Location:216 → 247
      LDLa; Low-density lipoprotein receptor domain class A

    3. NM_001104117.2 → NP_001097587.1  lost and found, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097587.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BIG2
      Conserved Domains (2) summary
      smart00192
      Location:216 → 247
      LDLa; Low-density lipoprotein receptor domain class A
      cl00049
      Location:121 → 209
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A6J3SW69 A0A6J3SW69
    Q5BIG2 Q5BIG2

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