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    TENM1 teneurin transmembrane protein 1 [ Gallus gallus (chicken) ]

    Gene ID: 395668, updated on 6-Jun-2024

    Summary

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    Official Symbol
    TENM1provided by CGNC
    Official Full Name
    teneurin transmembrane protein 1provided by CGNC
    Primary source
    CGNC:49426
    See related
    Ensembl:ENSGALG00010011658
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    ODZ1; TEN-1; ten-m1
    Orthologs
    human mouse all
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    Genomic context

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    See TENM1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (14636627..15483477)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (14669119..15516634)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112532362 Neighboring gene uncharacterized LOC107052094 Neighboring gene uncharacterized LOC112532396 Neighboring gene uncharacterized LOC121110638 Neighboring gene uncharacterized LOC121110639 Neighboring gene microRNA 6679 Neighboring gene SH2 domain containing 1A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Teneurin-1 is expressed in interconnected regions of the developing brain and is processed in vivo. Kenzelmann D, et al. BMC Dev Biol, 2008 Mar 25. PMID 18366734, Free PMC Article
    2. Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain. Minet AD, et al. J Cell Sci, 1999 Jun. PMID 10341219
    3. The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. Nunes SM, et al. Exp Cell Res, 2005 Apr 15. PMID 15777793
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Teneurin-1 and -2 are expressed by distinct interconnected populations of neurons in the developing central nervous system
      Title: Teneurin-1 is expressed in interconnected regions of the developing brain and is processed in vivo.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    teneurin-1
    Names
    odz, odd Oz/ten-m homolog 1
    odz, odd Oz/ten-m homolog 1(Drosophila)
    protein Odd Oz/ten-m homolog 1
    tenascin-M1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001397993.1 → NP_001384922.1  teneurin-1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000071
      UniProtKB/TrEMBL
      A0A8V0YAJ9, F1NN19
      Related
      ENSGALP00010016010.1, ENSGALT00010027904.1
      Conserved Domains (9) summary
      COG3209
      Location:1798 → 2367
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1170 → 1209
      NHL; NHL repeat [structural motif]
      cl18310
      Location:1141 → 1501
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1617 → 1649
      RHS_repeat; RHS Repeat
      pfam06484
      Location:23 → 298
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2621 → 2698
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:772 → 801
      acid_disulf_rpt; acidic double-disulfide repeat
      NF033759
      Location:516 → 740
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:692 → 733
      DSL; Delta serrate ligand

    2. NM_001397994.1 → NP_001384923.1  teneurin-1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000071
      UniProtKB/TrEMBL
      A0A8V0YAJ9, F1NN19
      Conserved Domains (9) summary
      COG3209
      Location:1798 → 2367
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1170 → 1209
      NHL; NHL repeat [structural motif]
      cl18310
      Location:1141 → 1501
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1617 → 1649
      RHS_repeat; RHS Repeat
      pfam06484
      Location:23 → 298
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2621 → 2698
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:772 → 801
      acid_disulf_rpt; acidic double-disulfide repeat
      NF033759
      Location:516 → 740
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:692 → 733
      DSL; Delta serrate ligand

    3. NM_204862.2 → NP_990193.2  teneurin-1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000071
      UniProtKB/TrEMBL
      A0A8V0YAJ9, F1NN19
      Related
      ENSGALP00010016005.1, ENSGALT00010027894.1
      Conserved Domains (9) summary
      COG3209
      Location:1798 → 2367
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1170 → 1209
      NHL; NHL repeat [structural motif]
      cl18310
      Location:1141 → 1501
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1617 → 1649
      RHS_repeat; RHS Repeat
      pfam06484
      Location:23 → 298
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2621 → 2698
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:772 → 801
      acid_disulf_rpt; acidic double-disulfide repeat
      NF033759
      Location:516 → 740
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:692 → 733
      DSL; Delta serrate ligand

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      14636627..15483477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046939904.1 → XP_046795860.1  teneurin-1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PWG0, A0A8V0YAJ9

    2. XM_015278189.4 → XP_015133675.1  teneurin-1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PWG0, A0A8V0YAJ9
      Related
      ENSGALP00010016007.1, ENSGALT00010027901.1
      Conserved Domains (10) summary
      COG3209
      Location:1806 → 2375
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1178 → 1217
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1838 → 1873
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2327 → 2405
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:577 → 713
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1625 → 1659
      RHS_repeat; RHS Repeat
      pfam06484
      Location:23 → 298
      Ten_N; Teneurin Intracellular Region
      pfam07974
      Location:513 → 539
      EGF_2; EGF-like domain
      pfam15636
      Location:2631 → 2706
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1149 → 1509
      NHL; NHL repeat unit of beta-propeller proteins

    3. XM_015278190.4 → XP_015133676.1  teneurin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YAJ9
      Conserved Domains (10) summary
      COG3209
      Location:1805 → 2374
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1177 → 1216
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1837 → 1872
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2326 → 2404
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:576 → 712
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1624 → 1658
      RHS_repeat; RHS Repeat
      pfam06484
      Location:23 → 298
      Ten_N; Teneurin Intracellular Region
      pfam07974
      Location:512 → 538
      EGF_2; EGF-like domain
      pfam15636
      Location:2630 → 2705
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1148 → 1508
      NHL; NHL repeat unit of beta-propeller proteins

    4. XM_040698712.2 → XP_040554646.1  teneurin-1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y5U3
      Related
      ENSGALP00010016006.1, ENSGALT00010027899.1
      Conserved Domains (5) summary
      COG3209
      Location:1719 → 2288
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:624 → 647
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1091 → 1130
      NHL; NHL repeat [structural motif]
      cl18310
      Location:1062 → 1422
      NHL; NHL repeat unit of beta-propeller proteins
      pfam01500
      Location:490 → 626
      Keratin_B2; Keratin, high sulfur B2 protein

    5. XM_046939905.1 → XP_046795861.1  teneurin-1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y5U3

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      14669119..15516634
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046915511.1 → XP_046771467.1  teneurin-1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PWG0, A0A8V0YAJ9

    2. XM_046915510.1 → XP_046771466.1  teneurin-1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PWG0, A0A8V0YAJ9

    3. XM_046915512.1 → XP_046771468.1  teneurin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YAJ9

    4. XM_046915513.1 → XP_046771469.1  teneurin-1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y5U3

    5. XM_046915514.1 → XP_046771470.1  teneurin-1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y5U3
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W6V6.1 GenPept UniProtKB/Swiss-Prot:Q9W6V6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.