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    ttbk-6 Inactive tau-tubulin kinase ttbk-6 [ Caenorhabditis elegans ]

    Gene ID: 183478, updated on 22-May-2024

    Summary

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    Gene symbol
    ttbk-6
    Gene description
    Inactive tau-tubulin kinase ttbk-6
    Primary source
    WormBase:WBGene00016673
    Locus tag
    CELE_C45G9.1
    See related
    AllianceGenome:WB:WBGene00016673
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in neurons. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ttbk-6 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (5074698..5075968)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene putative tRNA-dihydrouridine synthase-like protein C45G9.2 Neighboring gene Uncharacterized protein Neighboring gene Aldehyde dehydrogenase domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic overview of protein kinases. Manning G. WormBook, 2005 Dec 13. PMID 18050405, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Inactive tau-tubulin kinase ttbk-6
    NP_498080.1
    • Predicted

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5074698..5075968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065679.1 → NP_498080.1  Inactive tau-tubulin kinase ttbk-6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498080.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09503
      Conserved Domains (2) summary
      COG0515
      Location:2 → 287
      SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
      cl21453
      Location:1 → 231
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09503.2

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