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    Tango6 transport and golgi organization 6 homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307816, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Tango6provided by RGD
    Official Full Name
    transport and golgi organization 6 homologprovided by RGD
    Primary source
    RGD:1559841
    See related
    Ensembl:ENSRNOG00000022524 AllianceGenome:RGD:1559841
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1559841
    Summary
    Predicted to be involved in protein secretion. Orthologous to human TANGO6 (transport and golgi organization 6 homolog). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 55.7), Adrenal (RPKM 44.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tango6 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (51479384..51667142)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (34569588..34757362)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (38846204..39052940)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene cadherin 3 Neighboring gene cadherin 1 Neighboring gene hyaluronan synthase 3 Neighboring gene chromosome transmission fidelity factor 8 Neighboring gene DERPC proline and glycine rich nuclear protein Neighboring gene UTP4 small subunit processome component

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transport and Golgi organization protein 6 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427103.1 → NP_001414032.1  transport and Golgi organization protein 6 homolog

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A6IYX6, D4AAU1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      51479384..51667142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063278042.1 → XP_063134112.1  transport and Golgi organization protein 6 homolog isoform X1

      UniProtKB/TrEMBL
      A6IYX6

    2. XM_006255568.5 → XP_006255630.1  transport and Golgi organization protein 6 homolog isoform X2

      UniProtKB/TrEMBL
      A6IYX6, D4A9F1
      Related
      ENSRNOP00000059040.4
      Conserved Domains (3) summary
      pfam10304
      Location:973 → 1005
      RTP1_C2; Required for nuclear transport of RNA pol II C-terminus 2
      pfam10363
      Location:772 → 875
      RTP1_C1; Required for nuclear transport of RNA pol II C-terminus 1
      sd00044
      Location:810 → 838
      HEAT; HEAT repeat [structural motif]

    3. XM_039098139.2 → XP_038954067.1  transport and Golgi organization protein 6 homolog isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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