zftraf1 zinc finger TRAF-type containing 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zftraf1provided by ZNC
Official Full Name: zinc finger TRAF-type containing 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-060929-720
See related: Ensembl:ENSDARG00000061057 AllianceGenome:ZFIN:ZDB-GENE-060929-720
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cyhr1; fi59b02; wu:fi59b02; zgc:153061
Summary: Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm. Orthologous to human CYHR1 (cysteine and histidine rich 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (42918065..42928979, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (43349842..43359542, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fi59b02.x1 (e-PCR)
- UniSTS:197750

fc67a01.x1 (e-PCR)
- UniSTS:194222

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger TRAF-type-containing protein 1; cysteine and histidine-rich protein 1

Names: cysteine and histidine-rich protein 1-like; cysteine/histidine-rich 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001076740.1 → NP_001070208.1 zinc finger TRAF-type-containing protein 1

See identical proteins and their annotated locations for NP_001070208.1

Status: PROVISIONAL

Source sequence(s)

BC124233

UniProtKB/Swiss-Prot

F1R433, Q08CH8

Related

ENSDARP00000081094.5, ENSDART00000086659.6

Conserved Domains (1) summary

cl19105
Location:137 → 198

Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007130.7 Reference GRCz11 Primary Assembly

Range

42918065..42928979 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021468138.1 → XP_021323813.1 cysteine and histidine-rich protein 1 isoform X1

UniProtKB/TrEMBL

A0A8M9PB45

Conserved Domains (2) summary

cl17238
Location:11 → 43

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

cl19105
Location:53 → 114

Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...