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    hspa12a heat shock protein 12A [ Danio rerio (zebrafish) ]

    Gene ID: 751725, updated on 2-Jun-2024

    Summary

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    Official Symbol
    hspa12aprovided by ZNC
    Official Full Name
    heat shock protein 12Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031001-1
    See related
    Ensembl:ENSDARG00000070603 AllianceGenome:ZFIN:ZDB-GENE-031001-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153612
    Summary
    Orthologous to human HSPA12A (heat shock protein family A (Hsp70) member 12A). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    See hspa12a in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (21220702..21280360, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (21201066..21260396, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene phosphorylase, glycogen; brain Neighboring gene abhydrolase domain containing 12, lysophospholipase Neighboring gene enolase 4 Neighboring gene shootin 1 Neighboring gene ATPase, H+ transporting, lysosomal, V1 subunit B, member a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. p53 Protects Cells from Death at the Heatstroke Threshold Temperature. Gong L, et al. Cell Rep, 2019 Dec 10. PMID 31825845
    2. Comparative Study of the Molecular Characterization, Evolution, and Structure Modeling of Digestive Lipase Genes Reveals the Different Evolutionary Selection Between Mammals and Fishes. Tang SL, et al. Front Genet, 2022. PMID 35991544, Free PMC Article
    3. Shootins mediate collective cell migration and organogenesis of the zebrafish posterior lateral line system. Urasaki A, et al. Sci Rep, 2019 Aug 21. PMID 31434971, Free PMC Article
    4. Split top: a maternal cathepsin B that regulates dorsoventral patterning and morphogenesis. Langdon YG, et al. Development, 2016 Mar 15. PMID 26893345, Free PMC Article
    5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC153612

    General protein information

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    Preferred Names
    heat shock 70 kDa protein 12A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430854.1 → NP_001417783.1  heat shock 70 kDa protein 12A isoform 1

      Status: VALIDATED

      Source sequence(s)
      CU633972, CU634001, FQ377974

    2. NM_001430855.1 → NP_001417784.1  heat shock 70 kDa protein 12A isoform 2

      Status: VALIDATED

      Source sequence(s)
      CU633972, CU634001, FQ377974

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      21220702..21280360 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017351677.2 → XP_017207166.1  heat shock 70 kDa protein 12A isoform X3

      UniProtKB/TrEMBL
      A0A8M6YT54

    2. XM_017351675.2 → XP_017207164.1  heat shock 70 kDa protein 12A isoform X1

      UniProtKB/TrEMBL
      A0A8M6YVN3, F1Q8K1
      Related
      ENSDARP00000106960.2, ENSDART00000123198.4

    3. XM_017351676.2 → XP_017207165.1  heat shock 70 kDa protein 12A isoform X2

      UniProtKB/TrEMBL
      A0A2R8RN86, A0A8M6Z288
      Related
      ENSDARP00000149134.1, ENSDART00000181356.1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001045435.1: Suppressed sequence

      Description
      NM_001045435.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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