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    nucb1 nucleobindin 1 [ Danio rerio (zebrafish) ]

    Gene ID: 751753, updated on 25-Apr-2024

    Summary

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    Official Symbol
    nucb1provided by ZNC
    Official Full Name
    nucleobindin 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060825-222
    See related
    Ensembl:ENSDARG00000054833 AllianceGenome:ZFIN:ZDB-GENE-060825-222
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153192
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be located in Golgi apparatus and extracellular region. Predicted to be active in endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human NUCB1 (nucleobindin 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See nucb1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (30140591..30153276, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (30009749..30022416, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene neurotrophin-3-like Neighboring gene uncharacterized LOC103910259 Neighboring gene PTPRF interacting protein alpha 3 Neighboring gene cyclin Dx Neighboring gene TBC1 domain family, member 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Nesfatin-1-like peptide is a negative regulator of cardiovascular functions in zebrafish and goldfish. Sundarrajan L, et al. Gen Comp Endocrinol, 2021 Nov 1. PMID 34453930
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC153192

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    nucleobindin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045463.1 → NP_001038928.1  nucleobindin-1 precursor

      See identical proteins and their annotated locations for NP_001038928.1

      Status: PROVISIONAL

      Source sequence(s)
      BC122181
      UniProtKB/TrEMBL
      Q0P4B3
      Related
      ENSDARP00000071557.5, ENSDART00000077089.7
      Conserved Domains (1) summary
      pfam13499
      Location:239 → 312
      EF-hand_7; EF-hand domain pair

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      30140591..30153276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005163951.4 → XP_005164008.1  nucleobindin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BBG2
      Conserved Domains (1) summary
      pfam13499
      Location:239 → 312
      EF-hand_7; EF-hand domain pair
    Nucleotide Protein
    Heading Accession and Version

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