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    CG6614 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34583, updated on 10-May-2024

    Summary

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    Official Symbol
    CG6614provided by FlyBase
    Primary source
    FLYBASE:FBgn0032369
    Locus tag
    Dmel_CG6614
    See related
    AllianceGenome:FB:FBgn0032369
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6614
    Summary
    Human ortholog(s) of this gene implicated in spermatogenic failure 41. Orthologous to human CFAP70 (cilia and flagella associated protein 70). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG6614 in Genome Data Viewer
    Location:
    32F4-32F4; 2-44 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11644619..11648839, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11644619..11648839, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene kekkon 2 Neighboring gene Accessory gland-specific peptide 33A Neighboring gene sperm-associated antigen 4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    2. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848
    3. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article
    4. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article
    5. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cilium movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6614-PA
    CG6614-PB
    CG6614-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      11644619..11648839 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298916.1 → NP_001285845.1  uncharacterized protein Dmel_CG6614, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285845.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRL8, Q9VKG0
      Conserved Domains (2) summary
      sd00006
      Location:913 → 947
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:919 → 982
      TPR_11; TPR repeat

    2. NM_001298915.1 → NP_001285844.1  uncharacterized protein Dmel_CG6614, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285844.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2J5P7

    3. NM_135667.4 → NP_609511.3  uncharacterized protein Dmel_CG6614, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609511.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRL8, Q9VKG0
      Conserved Domains (2) summary
      sd00006
      Location:913 → 947
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:919 → 982
      TPR_11; TPR repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKG0 Q9VKG0
    X2J5P7 X2J5P7

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