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    Gm5127 predicted gene 5127 [ Mus musculus (house mouse) ]

    Gene ID: 331493, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Gm5127provided by MGI
    Official Full Name
    predicted gene 5127provided by MGI
    Primary source
    MGI:MGI:3648285
    See related
    Ensembl:ENSMUSG00000073010 AllianceGenome:MGI:3648285
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG331493; B130007I08
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Gm5127 in Genome Data Viewer
    Location:
    X D; X 47.36 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (105626774..105754163)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (106583170..106710557)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene fibronectin type III domain containing 3C1 pseudogene Neighboring gene fibronectin type III domain containing 3C1 Neighboring gene STARR-seq mESC enhancer starr_47737 Neighboring gene cysteinyl leukotriene receptor 1 Neighboring gene predicted gene, 24622 Neighboring gene STARR-seq mESC enhancer starr_47738 Neighboring gene predicted gene 14877 Neighboring gene zinc finger protein 277 pseudogene Neighboring gene predicted gene, 24491 Neighboring gene SNRPN upstream reading frame protein pseudogene Neighboring gene 60S ribosomal protein L37 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC331493

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033541.2 → NP_001028713.1  uncharacterized protein LOC331493

      See identical proteins and their annotated locations for NP_001028713.1

      Status: PREDICTED

      Source sequence(s)
      AK142438
      Consensus CDS
      CCDS30343.1
      UniProtKB/TrEMBL
      Q3UQH6
      Related
      ENSMUSP00000098855.4, ENSMUST00000101297.4
      Conserved Domains (2) summary
      cd14964
      Location:18 → 42
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:17 → 142
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      105626774..105754163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247617.3 → XP_011245919.1  uncharacterized protein LOC331493 isoform X1

      See identical proteins and their annotated locations for XP_011245919.1

      Conserved Domains (2) summary
      cd14964
      Location:31 → 57
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:31 → 156
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_011247618.2 → XP_011245920.1  uncharacterized protein LOC331493 isoform X1

      See identical proteins and their annotated locations for XP_011245920.1

      Conserved Domains (2) summary
      cd14964
      Location:31 → 57
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:31 → 156
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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