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    Yju2 YJU2 splicing factor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501285, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Yju2provided by RGD
    Official Full Name
    YJU2 splicing factorprovided by RGD
    Primary source
    RGD:1589601
    See related
    Ensembl:ENSRNOG00000047456 AllianceGenome:RGD:1589601
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ccdc94
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in RNA splicing. Predicted to be part of U2-type catalytic step 1 spliceosome. Orthologous to human YJU2 (YJU2 splicing factor homolog). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 131.0), Spleen (RPKM 100.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Yju2 in Genome Data Viewer
    Location:
    9q11
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (876790..886687)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (789603..799505)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (11098914..11108806, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 119b like Neighboring gene small nucleolar RNA SNORA48 Neighboring gene ribosomal protein S21, pseudogene 2 Neighboring gene Epstein-Barr virus induced 3 Neighboring gene uncharacterized LOC134480467 Neighboring gene src homology 2 domain-containing transforming protein D Neighboring gene fibronectin type III and SPRY domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Structure of a human catalytic step I spliceosome. Zhan X, et al. Science, 2018 Feb 2. PMID 29301961
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC156684

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in generation of catalytic spliceosome for first transesterification step IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U2-type catalytic step 1 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2-type catalytic step 1 spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    splicing factor YJU2
    Names
    YJU2 splicing factor homolog
    coiled-coil domain containing 94
    coiled-coil domain-containing protein 94

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109673.1 → NP_001103143.1  splicing factor YJU2

      See identical proteins and their annotated locations for NP_001103143.1

      Status: PROVISIONAL

      Source sequence(s)
      BC169032
      UniProtKB/TrEMBL
      A2VD11, A6KR23
      Related
      ENSRNOP00000067468.2, ENSRNOT00000072357.2
      Conserved Domains (2) summary
      COG5134
      Location:7 → 178
      COG5134; Uncharacterized conserved protein [Function unknown]
      pfam04502
      Location:8 → 262
      DUF572; Family of unknown function (DUF572)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      876790..886687
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244336.5 → XP_006244398.1  splicing factor YJU2 isoform X1

      UniProtKB/TrEMBL
      A6KR23
      Conserved Domains (2) summary
      COG5134
      Location:7 → 178
      COG5134; Uncharacterized conserved protein [Function unknown]
      pfam04502
      Location:8 → 177
      DUF572; Family of unknown function (DUF572)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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