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    sult1st3 sulfotransferase family 1, cytosolic sulfotransferase 3 [ Danio rerio (zebrafish) ]

    Gene ID: 368270, updated on 27-Mar-2024

    Summary

    Official Symbol
    sult1st3provided by ZNC
    Official Full Name
    sulfotransferase family 1, cytosolic sulfotransferase 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030804-28
    See related
    Ensembl:ENSDARG00000018361 AllianceGenome:ZFIN:ZDB-GENE-030804-28
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92322; wu:fj78b11
    Summary
    Enables sulfotransferase activity. Involved in xenobiotic metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; gastrointestinal system cancer (multiple); lung cancer (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to human SULT1A1 (sulfotransferase family 1A member 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See sult1st3 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (46559332..46581443, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (46551453..46573569, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene sulfotransferase family 1, cytosolic sulfotransferase 2 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 186 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 187 Neighboring gene taste receptor, type 1, member 2, tandem duplicate 1 Neighboring gene taste receptor, type 1, member 2, tandem duplicate 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables aryl sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within catecholamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within steroid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sulfation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cytosolic sulfotransferase 3
    Names
    SULT1 ST3
    NP_899191.2
    XP_005172522.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183348.2NP_899191.2  cytosolic sulfotransferase 3

      See identical proteins and their annotated locations for NP_899191.2

      Status: PROVISIONAL

      Source sequence(s)
      BC076007
      UniProtKB/Swiss-Prot
      Q7T2V2
      UniProtKB/TrEMBL
      A0A8M1P8Q6, E7F5H9, Q6DHG7
      Related
      ENSDARP00000030002.3, ENSDART00000030470.4
      Conserved Domains (1) summary
      pfam00685
      Location:43294
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      46559332..46581443 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005172465.2XP_005172522.1  cytosolic sulfotransferase 3 isoform X1

      See identical proteins and their annotated locations for XP_005172522.1

      UniProtKB/Swiss-Prot
      Q7T2V2
      UniProtKB/TrEMBL
      A0A8M1P8Q6, E7F5H9, Q6DHG7
      Related
      ENSDARP00000006665.8, ENSDART00000014240.10
      Conserved Domains (1) summary
      pfam00685
      Location:43294
      Sulfotransfer_1; Sulfotransferase domain