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    Zbtb9 zinc finger and BTB domain containing 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294289, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Zbtb9provided by RGD
    Official Full Name
    zinc finger and BTB domain containing 9provided by RGD
    Primary source
    RGD:1303050
    See related
    Ensembl:ENSRNOG00000026799 AllianceGenome:RGD:1303050
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    3930402F13Rik
    Summary
    Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZBTB9 (zinc finger and BTB domain containing 9). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 48.6), Spleen (RPKM 40.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zbtb9 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (5059296..5069422)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (5057433..5060459)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (5566517..5569535)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene synaptic Ras GTPase activating protein 1 Neighboring gene cutA divalent cation tolerance homolog Neighboring gene uncharacterized LOC120098811 Neighboring gene BCL2-antagonist/killer 1 Neighboring gene gametogenetin binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis. Li ZZ, et al. Biosci Rep, 2020 Jan 31. PMID 31904090, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and BTB domain-containing protein 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213564.4 → NP_998729.1  zinc finger and BTB domain-containing protein 9

      See identical proteins and their annotated locations for NP_998729.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      A0A0U1RRY9, Q6MGD2
      Related
      ENSRNOP00000000574.4, ENSRNOT00000000574.7
      Conserved Domains (3) summary
      sd00017
      Location:380 → 397
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl38908
      Location:30 → 140
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
      pfam00096
      Location:405 → 425
      zf-C2H2; Zinc finger, C2H2 type

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      5059296..5069422
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017601590.3 → XP_017457079.1  zinc finger and BTB domain-containing protein 9 isoform X1

      UniProtKB/TrEMBL
      A0A0U1RRY9, Q6MGD2
      Conserved Domains (3) summary
      sd00017
      Location:380 → 397
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl38908
      Location:30 → 140
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
      pfam00096
      Location:405 → 425
      zf-C2H2; Zinc finger, C2H2 type

    2. XM_039098512.2 → XP_038954440.1  zinc finger and BTB domain-containing protein 9 isoform X1

      UniProtKB/TrEMBL
      A0A0U1RRY9, Q6MGD2
      Conserved Domains (3) summary
      sd00017
      Location:380 → 397
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl38908
      Location:30 → 140
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
      pfam00096
      Location:405 → 425
      zf-C2H2; Zinc finger, C2H2 type

    3. XM_006256122.4 → XP_006256184.1  zinc finger and BTB domain-containing protein 9 isoform X1

      See identical proteins and their annotated locations for XP_006256184.1

      UniProtKB/TrEMBL
      A0A0U1RRY9, Q6MGD2
      Related
      ENSRNOP00000088894.1
      Conserved Domains (3) summary
      sd00017
      Location:380 → 397
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl38908
      Location:30 → 140
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
      pfam00096
      Location:405 → 425
      zf-C2H2; Zinc finger, C2H2 type
    Nucleotide Protein Strain
    Heading Accession and Version

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