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    Mdp1 magnesium-dependent phosphatase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290230, updated on 13-Apr-2024

    Summary

    Official Symbol
    Mdp1provided by RGD
    Official Full Name
    magnesium-dependent phosphatase 1provided by RGD
    Primary source
    RGD:1311147
    See related
    Ensembl:ENSRNOG00000019840 AllianceGenome:RGD:1311147
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mdp-1; RGD1311147
    Summary
    Enables phosphatase activity. Involved in fructosamine metabolic process. Orthologous to human MDP1 (magnesium dependent phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 44.4), Spleen (RPKM 30.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Mdp1 in Genome Data Viewer
    Location:
    15p13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (33118944..33121817, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (29148994..29151868, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (34336058..34340078, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene transmembrane 9 superfamily member 1 Neighboring gene testis-specific serine kinase 4 Neighboring gene NEDD8 ubiquitin like modifier Neighboring gene guanosine monophosphate reductase 2 Neighboring gene TERF1 interacting nuclear factor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables acid phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in fructosamine metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    magnesium-dependent phosphatase 1
    NP_001099509.1
    NP_001388557.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106039.2NP_001099509.1  magnesium-dependent phosphatase 1 isoform 2

      See identical proteins and their annotated locations for NP_001099509.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A6KH31
      Conserved Domains (1) summary
      pfam12689
      Location:3160
      Acid_PPase; Acid Phosphatase
    2. NM_001401628.1NP_001388557.1  magnesium-dependent phosphatase 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      D4A4U3
      Related
      ENSRNOP00000026914.4, ENSRNOT00000026914.5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      33118944..33121817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)