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    rnf183 ring finger protein 183 [ Danio rerio (zebrafish) ]

    Gene ID: 767730, updated on 27-Mar-2024

    Summary

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    Official Symbol
    rnf183provided by ZNC
    Official Full Name
    ring finger protein 183provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-1090
    See related
    Ensembl:ENSDARG00000068851 AllianceGenome:ZFIN:ZDB-GENE-060929-1090
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153310
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to several human genes including RNF225 (ring finger protein 225). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See rnf183 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (34881579..34893138, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (35028511..35034726, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene SH3-binding domain protein 5-like, a Neighboring gene alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase a Neighboring gene DEAH (Asp-Glu-Ala-His) box polypeptide 16 Neighboring gene palmitoyl-protein thioesterase 2a, tandem duplicate 2 Neighboring gene palmitoyl-protein thioesterase 2a, tandem duplicate 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The zebrafish maternal-effect gene mission impossible encodes the DEAH-box helicase Dhx16 and is essential for the expression of downstream endodermal genes. Putiri E, et al. Dev Biol, 2011 May 15. PMID 21396359, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC153310

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF183; uncharacterized protein LOC767730
    NP_001070136.1
    XP_021337146.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076668.1 → NP_001070136.1  E3 ubiquitin-protein ligase RNF183

      See identical proteins and their annotated locations for NP_001070136.1

      Status: PREDICTED

      Source sequence(s)
      BC124313
      UniProtKB/TrEMBL
      Q08CB0
      Related
      ENSDARP00000090494.2, ENSDART00000099721.4
      Conserved Domains (1) summary
      cd00162
      Location:106 → 157
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      34881579..34893138 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021481471.1 → XP_021337146.1  uncharacterized protein LOC767730 isoform X1

      UniProtKB/TrEMBL
      A0A8M9QLI5
      Conserved Domains (1) summary
      cl17238
      Location:106 → 157
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    Nucleotide Protein Strain
    Heading Accession and Version

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