ptgdsb.1 prostaglandin D2 synthase b, tandem duplicate 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ptgdsb.1provided by ZNC
Official Full Name: prostaglandin D2 synthase b, tandem duplicate 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-8436
See related: Ensembl:ENSDARG00000027088 AllianceGenome:ZFIN:ZDB-GENE-030131-8436
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ptgds; ptgdsb; hm:zeh0800; wu:fb10b10; wu:fb11h03
Summary: Enables retinoic acid binding activity. Predicted to be located in extracellular region. Is expressed in eye; female organism; male organism; postcranial axial skeleton; and reproductive system. Human ortholog(s) of this gene implicated in carotid artery disease; intrahepatic cholangiocarcinoma; and urinary tract infection. Orthologous to several human genes including PTGDS (prostaglandin D2 synthase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 24

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (17027313..17029335, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (16882894..16884916, complement)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The temporal expression of ptgds was investigated in the microdissected gonads, however, no differential expression that could indicate sex-specific difference between individual juvenile zebrafish was observed.
Title: Expression of prostaglandin synthases (pgds and pges) during zebrafish gonadal differentiation.

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General gene information

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Markers

fb10b10.x1 (e-PCR)
- UniSTS:202800

fb11h03.x1 (e-PCR)
- UniSTS:202851

fc38f04.x1 (e-PCR)
- UniSTS:193737

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
NOT enables prostaglandin-D synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables prostaglandin-D synthase activity	IEA Inferred from Electronic Annotation more info
enables retinoic acid binding	IDA Inferred from Direct Assay more info	PubMed
enables small molecule binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: prostaglandin D2 synthase b, tandem duplicate 1

Names: L-PGDS

NP_998799.1

EC 5.3.99.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213634.1 → NP_998799.1 prostaglandin D2 synthase b, tandem duplicate 1 precursor

See identical proteins and their annotated locations for NP_998799.1

Status: PROVISIONAL

Source sequence(s)

AB071601

UniProtKB/TrEMBL

B2GR30, Q8QGV5

Related

ENSDARP00000037484.6, ENSDART00000039267.7

Conserved Domains (1) summary

pfam00061
Location:35 → 176

Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family