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    adss1 adenylosuccinate synthase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 407989, updated on 27-Mar-2024

    Summary

    Official Symbol
    adss1provided by ZNC
    Official Full Name
    adenylosuccinate synthase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040516-18
    See related
    Ensembl:ENSDARG00000099517 AllianceGenome:ZFIN:ZDB-GENE-040516-18
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    AdSS 1; adssl1; zgc:85738
    Summary
    Predicted to enable adenylosuccinate synthase activity. Acts upstream of or within muscle cell cellular homeostasis and skeletal muscle fiber development. Predicted to be active in cytoplasm. Orthologous to human ADSS1 (adenylosuccinate synthase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See adss1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (1323699..1355792)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (663433..695526)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 17 Neighboring gene cdc42 effector protein 3-like Neighboring gene inverted formin 2 Neighboring gene SIVA1, apoptosis-inducing factor Neighboring gene zinc finger and BTB domain containing 42

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables adenylosuccinate synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables adenylosuccinate synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables adenylosuccinate synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in 'de novo' AMP biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in 'de novo' AMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within AMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in IMP metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within muscle cell cellular homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within purine nucleotide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within skeletal muscle fiber development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    adenylosuccinate synthetase isozyme 1
    Names
    adenylosuccinate synthase like 1
    NP_999985.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214820.1NP_999985.1  adenylosuccinate synthetase isozyme 1

      See identical proteins and their annotated locations for NP_999985.1

      Status: PROVISIONAL

      Source sequence(s)
      BC070009
      UniProtKB/Swiss-Prot
      Q6NSN5
      Related
      ENSDARP00000136105.2, ENSDART00000172540.2
      Conserved Domains (1) summary
      pfam00709
      Location:34453
      Adenylsucc_synt; Adenylosuccinate synthetase

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      1323699..1355792
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)