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    PRORSD1P prolyl-tRNA synthetase associated domain containing 1, pseudogene [ Homo sapiens (human) ]

    Gene ID: 344405, updated on 17-Jun-2024

    Summary

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    Official Symbol
    PRORSD1Pprovided by HGNC
    Official Full Name
    prolyl-tRNA synthetase associated domain containing 1, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:34379
    See related
    Ensembl:ENSG00000293422 AllianceGenome:HGNC:34379
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ProX; Ybakd1; Prdxdd1; PRDXDD1P; ProXp-ala; NCRNA00117
    Summary
    Predicted to enable aminoacyl-tRNA editing activity. Predicted to be involved in aminoacyl-tRNA metabolism involved in translational fidelity. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See PRORSD1P in Genome Data Viewer
    Location:
    2p16.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (55282319..55284472)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (55279543..55281678)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (55509455..55511608)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene clathrin heavy chain linker domain containing 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15777 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15778 Neighboring gene ribosomal protein S27a Neighboring gene mitochondrial translational initiation factor 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:55496405-55497228 Neighboring gene Sharpr-MPRA regulatory regions 8685 and 822 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:55508487-55509380 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:55509381-55510272 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:55516372-55516872 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:55516873-55517373 Neighboring gene Sharpr-MPRA regulatory region 7699 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15780 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:55530138-55530638 Neighboring gene coiled-coil domain containing 88A Neighboring gene uncharacterized LOC124907768 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:55635985-55636565 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11497 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11498 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11499 Neighboring gene basic transcription factor 3 pseudogene 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Human cytoplasmic ProX edits mischarged tRNAPro with amino acid but not tRNA specificity. Ruan LL, et al. Biochem J, 2013 Feb 15. PMID 23210460
    2. The sequence of the human genome. Venter JC, et al. Science, 2001 Feb 16. PMID 11181995
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Human cytoplasmic ProX edits mischarged tRNAPro with amino acid but not tRNA specificity
      Title: Human cytoplasmic ProX edits mischarged tRNAPro with amino acid but not tRNA specificity.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Other Names

    • PrdX deacylase domain containing 1, pseudogene
    • YBak domain containing 1
    • prolyl-tRNA synthetase domain containing 1, pseudogene

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in aminoacyl-tRNA metabolism involved in translational fidelity IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_027258.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC012358
      Related
      ENST00000563365.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      55282319..55284472
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      55279543..55281678
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001080459.1: Suppressed sequence

      Description
      NM_001080459.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6NEY8.3 GenPept UniProtKB/Swiss-Prot:A6NEY8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials