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    ppp6r3 protein phosphatase 6, regulatory subunit 3 [ Danio rerio (zebrafish) ]

    Gene ID: 324530, updated on 27-Mar-2024

    Summary

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    Official Symbol
    ppp6r3provided by ZNC
    Official Full Name
    protein phosphatase 6, regulatory subunit 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3251
    See related
    Ensembl:ENSDARG00000013379 AllianceGenome:ZFIN:ZDB-GENE-030131-3251
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    saps3; fc43a07; zgc:56113; im:7145792; wu:fc31g07; wu:fc43a07
    Summary
    Predicted to enable protein phosphatase regulator activity. Predicted to be involved in regulation of phosphoprotein phosphatase activity. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including PPP6R3 (protein phosphatase 6 regulatory subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See ppp6r3 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (10602229..10629972, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (10505423..10533697, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene si:ch211-107e6.5 Neighboring gene si:ch211-107e6.6 Neighboring gene uncharacterized LOC110437781 Neighboring gene low density lipoprotein receptor-related protein 5 Neighboring gene wu:fa25f02

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0685

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein phosphatase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of phosphoprotein phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine-protein phosphatase 6 regulatory subunit 3
    Names
    SAPS domain family, member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199684.2 → NP_955978.2  serine/threonine-protein phosphatase 6 regulatory subunit 3

      Status: VALIDATED

      Source sequence(s)
      CR391967, EB947260, EB960336
      UniProtKB/TrEMBL
      A0A8M1PEC6, X1WG48
      Related
      ENSDARP00000129203.1, ENSDART00000155231.3
      Conserved Domains (1) summary
      pfam04499
      Location:128 → 516
      SAPS; SIT4 phosphatase-associated protein

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      10602229..10629972 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009297820.3 → XP_009296095.1  serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X6

      UniProtKB/TrEMBL
      A0A8M3AWD6
      Conserved Domains (1) summary
      pfam04499
      Location:128 → 516
      SAPS; SIT4 phosphatase-associated protein

    2. XM_009297822.3 → XP_009296097.1  serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X8

      UniProtKB/TrEMBL
      A0A8M3B701
      Conserved Domains (1) summary
      pfam04499
      Location:128 → 516
      SAPS; SIT4 phosphatase-associated protein

    3. XM_009297818.3 → XP_009296093.1  serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X4

      UniProtKB/TrEMBL
      A0A8M3APJ9
      Conserved Domains (1) summary
      pfam04499
      Location:128 → 516
      SAPS; SIT4 phosphatase-associated protein

    4. XM_009297814.3 → XP_009296089.1  serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X2

      UniProtKB/TrEMBL
      A0A286YB73, A0A8M3ANY0
      Related
      ENSDARP00000151649.1, ENSDART00000181722.1
      Conserved Domains (1) summary
      pfam04499
      Location:128 → 516
      SAPS; SIT4 phosphatase-associated protein

    5. XM_009297819.3 → XP_009296094.1  serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X5

      UniProtKB/TrEMBL
      A0A8M3AZH6
      Conserved Domains (1) summary
      pfam04499
      Location:128 → 520
      SAPS; SIT4 phosphatase-associated protein

    6. XM_009297817.3 → XP_009296092.1  serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X3

      UniProtKB/TrEMBL
      A0A8M3B6Z8
      Conserved Domains (1) summary
      pfam04499
      Location:128 → 520
      SAPS; SIT4 phosphatase-associated protein

    7. XM_009297811.3 → XP_009296086.1  serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1

      See identical proteins and their annotated locations for XP_009296086.1

      UniProtKB/TrEMBL
      A0A8M3AWD3
      Conserved Domains (1) summary
      pfam04499
      Location:128 → 520
      SAPS; SIT4 phosphatase-associated protein

    8. XM_009297821.3 → XP_009296096.1  serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X7

      UniProtKB/TrEMBL
      A0A8M3ANY4
      Related
      ENSDARP00000128171.1, ENSDART00000155375.3
      Conserved Domains (1) summary
      pfam04499
      Location:128 → 516
      SAPS; SIT4 phosphatase-associated protein
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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