rab25a RAB25, member RAS oncogene family a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rab25aprovided by ZNC
Official Full Name: RAB25, member RAS oncogene family aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041212-69
See related: Ensembl:ENSDARG00000058800 AllianceGenome:ZFIN:ZDB-GENE-041212-69
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rab25; zgc:101648; si:dkeyp-84f11.7
Summary: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in exocytosis. Predicted to be active in recycling endosome. Orthologous to human RAB25 (RAB25, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (7413606..7420863, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (7494681..7501938, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium.
Title: The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cortical actin cytoskeleton organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of cytokinesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of endocytic recycling	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in recycling endosome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ras-related protein Rab-25a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008641.2 → NP_001008641.2 ras-related protein Rab-25a

See identical proteins and their annotated locations for NP_001008641.2

Status: VALIDATED

Source sequence(s)

EH456340, FP085396

UniProtKB/TrEMBL

A0A8M1N3T9, Q1LVA5

Related

ENSDARP00000076180.2, ENSDART00000081741.4

Conserved Domains (2) summary

smart00175
Location:11 → 174

RAB; Rab subfamily of small GTPases

cd01868
Location:9 → 172

Rab11_like; Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25