naxe NAD(P)HX epimerase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: naxeprovided by ZNC
Official Full Name: NAD(P)HX epimeraseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-362
See related: Ensembl:ENSDARG00000058806 AllianceGenome:ZFIN:ZDB-GENE-040718-362
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: apoa1bp; zgc:92263
Summary: Predicted to enable NADHX epimerase activity. Predicted to act upstream of or within lipid transport. Predicted to be located in extracellular region. Predicted to be active in mitochondrion. Orthologous to human NAXE (NAD(P)HX epimerase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (7408275..7412647)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (7489350..7493722)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

findings demonstrate that secreted AIBP positively regulates cholesterol efflux from endothelial cells and that effective cholesterol efflux is critical for proper angiogenesis [AIBP]
Title: Control of angiogenesis by AIBP-mediated cholesterol efflux.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables NADHX epimerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables NADHX epimerase activity	IEA Inferred from Electronic Annotation more info
enables NADPHX epimerase activity	IEA Inferred from Electronic Annotation more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within lipid transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: NAD(P)H-hydrate epimerase

Names: aibp1; apolipoprotein A-I binding protein

NP_001002618.1

EC 5.1.99.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.