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    ccdc22 coiled-coil domain containing 22 [ Danio rerio (zebrafish) ]

    Gene ID: 556259, updated on 27-Mar-2024

    Summary

    Official Symbol
    ccdc22provided by ZNC
    Official Full Name
    coiled-coil domain containing 22provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050913-93
    See related
    Ensembl:ENSDARG00000052379 AllianceGenome:ZFIN:ZDB-GENE-050913-93
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:114058
    Summary
    Predicted to enable cullin family protein binding activity. Predicted to be involved in positive regulation of ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within protein transport. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome 2. Orthologous to human CCDC22 (coiled-coil domain containing 22). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See ccdc22 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (23615149..23638012)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (23593910..23616773)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene WASP actin nucleation promoting factor b Neighboring gene solute carrier family 38 member 5b Neighboring gene 5'-nucleotidase domain containing 2 Neighboring gene transfer RNA histidin (anticodon GUG)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC114058

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cullin family protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025485.1NP_001020656.1  coiled-coil domain-containing protein 22

      See identical proteins and their annotated locations for NP_001020656.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097121
      UniProtKB/Swiss-Prot
      Q4V909
      Related
      ENSDARP00000090542.4, ENSDART00000099769.6
      Conserved Domains (1) summary
      pfam05667
      Location:1602
      DUF812; Protein of unknown function (DUF812)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      23615149..23638012
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)