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    AT4G19520 disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827694, updated on 15-Feb-2024

    Summary

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    Gene symbol
    AT4G19520
    Gene description
    disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    Araport:AT4G19520
    Locus tag
    AT4G19520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F24J7.80; F24J7_80
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    Genomic context

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    See AT4G19520 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Sequence:
    Chromosome: 4; NC_003075.7 (10639269..10647280, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene nucleoside-triphosphatase/transmembrane receptor/nucleotide binding/ATP binding protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) Neighboring gene disease resistance protein (TIR-NBS-LRR class) family Neighboring gene zinc ion binding / transcription regulator Neighboring gene INDH1(iron-sulfur protein required for NADH dehydrogenase)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The AP2/ERF transcription factor AtERF73/HRE1 modulates ethylene responses during hypoxia in Arabidopsis. Yang CY, et al. Plant Physiol, 2011 May. PMID 21398256, Free PMC Article
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001341353.1
    NM_001341354.1
    NM_001341355.1
    NM_118072.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NAD+ nucleotidase, cyclic ADP-ribose generating IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADP+ nucleosidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    disease resistance protein (TIR-NBS-LRR class) family
    NP_193687.3
    • disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT3G51560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      10639269..10647280 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001341352.1 → NP_001329580.1  disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UWB5, A0A1P8B850

    2. NM_118072.4 → NP_193687.3  disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193687.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JT82, O49470
      UniProtKB/TrEMBL
      A0A5S9XUE9
      Conserved Domains (4) summary
      COG4886
      Location:748 → 1062
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:757 → 780
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:602 → 627
      LRR_AMN1; leucine-rich repeat [structural motif]
      cl27891
      Location:6 → 885
      LRR_3; Leucine Rich Repeat

    3. NM_001341353.1 → NP_001329583.1  disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B852, A0A654FQW1

    4. NM_001341354.1 → NP_001329581.1  disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UWB5, A0A1P8B850

    5. NM_001341355.1 → NP_001329582.1  disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B854, A0A654FQW1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JT82.1

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