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    Galnt14 polypeptide N-acetylgalactosaminyltransferase 14 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313878, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Galnt14provided by RGD
    Official Full Name
    polypeptide N-acetylgalactosaminyltransferase 14provided by RGD
    Primary source
    RGD:1310068
    See related
    Ensembl:ENSRNOG00000007951 AllianceGenome:RGD:1310068
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable carbohydrate binding activity; metal ion binding activity; and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Orthologous to human GALNT14 (polypeptide N-acetylgalactosaminyltransferase 14). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 83.2), Brain (RPKM 26.8) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Galnt14 in Genome Data Viewer
    Location:
    6q14
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (27507878..27724033)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (21756039..21977533)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (24770308..24985711, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103483 Neighboring gene EH-domain containing 3 Neighboring gene uncharacterized LOC134479329 Neighboring gene calpain 13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polypeptide N-acetylgalactosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    polypeptide N-acetylgalactosaminyltransferase 14
    Names
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
    NP_001012109.1
    XP_038968091.1
    XP_038968092.1
    XP_063117931.1
    XP_063117932.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012109.1 → NP_001012109.1  polypeptide N-acetylgalactosaminyltransferase 14

      See identical proteins and their annotated locations for NP_001012109.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079128
      UniProtKB/TrEMBL
      A0A8I5ZTB2, A6H9Z9, F7F293, Q6AYA4
      Related
      ENSRNOP00000010613.5, ENSRNOT00000010613.7
      Conserved Domains (4) summary
      cd02510
      Location:114 → 408
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      cd00161
      Location:422 → 549
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:422 → 547
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
      pfam13641
      Location:111 → 337
      Glyco_tranf_2_3; Glycosyltransferase like family 2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      27507878..27724033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261862.1 → XP_063117932.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZTB2, A0A8I5ZTM0

    2. XM_063261861.1 → XP_063117931.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZTB2

    3. XM_039112163.2 → XP_038968091.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZTB2
      Conserved Domains (2) summary
      cd02510
      Location:86 → 380
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:394 → 519
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    4. XM_039112164.2 → XP_038968092.1  polypeptide N-acetylgalactosaminyltransferase 14 isoform X3

      Conserved Domains (2) summary
      cd02510
      Location:2 → 269
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:283 → 408
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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